Lomonosov Moscow State University, Moscow, Russia.
Dokl Biochem Biophys. 2024 Oct;518(1):417-419. doi: 10.1134/S1607672924701096. Epub 2024 Aug 28.
Mice of two strains selected for successful solution of "object permanence" test and for lack of such solution demonstrated the differential reaction to injections of two drugs. The effects of injections of atomoxetine. which blocks the noradrenaline reuptake, and of 'non-benzodiazepine" anxiolytic afobazol was different. The success of solutions increased in mice selected for this test "non-solution": and decreased or was inefficient in mice, selected for successful solution of object permanence cognitive test.
两种品系的小鼠被分别用于“客体永久性”测试的成功解决和缺乏这种解决方法的研究。这两种品系的小鼠对两种药物的注射表现出不同的反应。去甲肾上腺素再摄取抑制剂托莫西汀和“非苯二氮䓬类”抗焦虑药阿普唑仑的注射效果不同。在选择用于此测试的“非解决方案”的小鼠中，解决方案的成功率增加，而在选择用于成功解决客体永久性认知测试的小鼠中，成功率降低或无效。
