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神经毒素和联合疗法。

Neurotoxins and Combination Therapies.

机构信息

University of Arkansas for Medical Sciences, Little Rock, AR.

Dermatology Associates of Plymouth Meeting, Plymouth Meeting, Plymouth Meeting, PA.

出版信息

Dermatol Surg. 2024 Sep 1;50(9S):S85-S90. doi: 10.1097/DSS.0000000000004359. Epub 2024 Jul 31.

DOI:10.1097/DSS.0000000000004359
PMID:39196840
Abstract

BACKGROUND

Facial aging involves multilevel changes, extending from the skin to deep support structures. A comprehensive treatment approach targeting the many aspects of facial dynamics and architecture is often necessary to achieve optimal correction, prevent changes before they occur, and/or help highlight inherited features.

OBJECTIVE

To explore the integration of botulinum toxin type A (BoNT-A) into multimodal aesthetic treatment plans.

MATERIALS AND METHODS

This article reviews evidence supporting the combination of BoNT-A with other minimally invasive cosmetic therapies, including dermal fillers, lasers, and energy-based devices as well as with plastic and reconstructive surgeries for more controlled healing and improved scar cosmesis.

RESULTS

Combination treatment protocols including BoNT-A demonstrate higher patient satisfaction and retention rates compared to monotherapy or sequential treatments. Some guidelines for sequencing of treatments exist, but evidence is scant with certain combinations.

CONCLUSION

Integrating BoNT-A into a larger aesthetic treatment plan is crucial for achieving natural and satisfying results in facial rejuvenation. Evidence supports better outcomes when incorporating with both surgical and nonsurgical modalities. Understanding how to address anatomy over time through different aesthetic therapies together allows for individually tailored, more deeply impactful treatment plans.

摘要

背景

面部衰老涉及多层次的变化,从皮肤延伸到深层支撑结构。为了达到最佳矫正效果、预防变化的发生,以及/或帮助凸显遗传特征,通常需要一种针对面部动态和结构多方面的综合治疗方法。

目的

探讨将肉毒毒素 A 型(BoNT-A)纳入多模态美容治疗计划的方法。

材料和方法

本文回顾了支持 BoNT-A 与其他微创美容疗法联合应用的证据,包括真皮填充剂、激光和能量设备,以及与整形和重建手术联合应用,以实现更可控的愈合和改善疤痕美容效果。

结果

与单一疗法或序贯疗法相比,包含 BoNT-A 的联合治疗方案显示出更高的患者满意度和保留率。存在一些关于治疗顺序的指南,但某些组合的证据仍然不足。

结论

将 BoNT-A 纳入更大的美容治疗计划对于实现面部年轻化的自然和满意效果至关重要。有证据表明,将其与手术和非手术方式结合使用可以获得更好的效果。通过不同的美容疗法共同了解如何随时间解决解剖结构问题,可以制定出更具个性化、更有深度的治疗方案。

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Neurotoxins and Combination Therapies.神经毒素和联合疗法。
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