DeNova Research, Chicago, Illinois.
Chicago Center for Facial Plastic Surgery, Chicago, Illinois.
J Cosmet Dermatol. 2019 Jun;18(3):798-805. doi: 10.1111/jocd.12977. Epub 2019 Apr 29.
Cosmeceutical therapies including face washes, moisturizers, chemical peels and antioxidant formulations are intended to improve the esthetic appearance of skin. The use of these products as adjuncts to full facial rejuvenation with hyaluronic acid filler and abobotulinumtoxinA may improve cosmetic and socio-esthetic outcomes.
To characterize the effect of skin care products in subjects undergoing full facial rejuvenation with abobotulinumtoxinA and hyaluronic acid in improving facial skin appearance, patient satisfaction, and projected first impressions.
Twenty subjects were recruited and divided into two treatment groups. Subjects in Group A followed a standard skin care regimen, whereas subjects in Group B received a more robust skin care regimen including chemical peels and antioxidant formulations. All subjects underwent facial rejuvenation treatments with hyaluronic acid at Visit 2 and with abobotulinumtoxinA at Visit 7. Patient esthetic improvement, satisfaction, self-esteem, and first impression were evaluated via the Fitzpatrick Wrinkle Assessment Scale, Global Aesthetic Improvement Scale, Skin Quality Assessment, Heatherton & Polivy State Self-Esteem Scale, Subject Satisfaction Scale, and the First Impressions Questionnaire.
Both treatment groups experienced significant improvements in the Skin Quality Assessment, Fitzpatrick Wrinkle Assessment Scale, Heatherton and Polivy State Self-Esteem Scale, and First Impressions Questionnaire.
The cosmeceutical therapies used in this study in combination with abobotulinumtoxinA and hyaluronic acid filler improved subjects' skin quality, self-esteem, and projected first impressions. Larger studies are needed to determine the most efficacious combination of topical skin therapies with facial rejuvenation therapy.
美容护肤品（包括洗面奶、保湿霜、化学换肤和抗氧化制剂）旨在改善皮肤的美观外观。将这些产品作为透明质酸填充剂和 abobotulinumtoxinA 进行全面面部年轻化治疗的辅助手段，可能会改善美容和社会审美效果。
描述在接受 abobotulinumtoxinA 和透明质酸全面面部年轻化治疗的患者中，使用护肤品对面部皮肤外观、患者满意度和第一印象的影响。
招募了 20 名受试者，并将其分为两组。A 组患者遵循标准的护肤方案，而 B 组患者则接受更强化的护肤方案，包括化学换肤和抗氧化制剂。所有受试者在第 2 次就诊时接受透明质酸面部年轻化治疗，在第 7 次就诊时接受 abobotulinumtoxinA 治疗。通过 Fitzpatrick 皱纹评估量表、整体美容改善量表、皮肤质量评估、Heatherton 和 Polivy 状态自尊量表、患者满意度量表和第一印象问卷评估患者的美容改善、满意度、自尊和第一印象。
两组患者的皮肤质量评估、Fitzpatrick 皱纹评估量表、Heatherton 和 Polivy 状态自尊量表以及第一印象问卷均有显著改善。
本研究中使用的美容护肤品与 abobotulinumtoxinA 和透明质酸填充剂联合使用，改善了患者的皮肤质量、自尊和预期第一印象。需要更大规模的研究来确定最有效的局部皮肤治疗与面部年轻化治疗的组合。
