引导赖氨酸特异性去甲基化酶1忽略乙酰化作用。
Coaching LSD1 to ignore acetylation.
作者信息
Black Joshua C, Kutateladze Tatiana G
机构信息
Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO, USA.
出版信息
Nat Chem Biol. 2025 Feb;21(2):162-163. doi: 10.1038/s41589-024-01710-5.
Abstract
Engineered demethylase LSD1 opens a new avenue in developing tools to study intricate relationships between histone post-translational modifications that can be enzymatically edited.
摘要
工程化去甲基化酶LSD1为开发工具研究可通过酶促编辑的组蛋白翻译后修饰之间的复杂关系开辟了一条新途径。
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