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基于轻量化深度学习模型的急性胆源性胰腺炎早期内镜治疗效果的荟萃分析。

Meta-analysis of the effectiveness of early endoscopic treatment of Acute biliary pancreatitis based on lightweight deep learning model.

机构信息

Department of Hepatopancreatobiliary Surgery, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang NO.1 People's Hospital, Jiujiang, 332000, Jiangxi, China.

Department of Gastroenterology, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang NO.1 People's Hospital, Jiujiang, 332000, Jiangxi, China.

出版信息

BMC Gastroenterol. 2024 Aug 28;24(1):292. doi: 10.1186/s12876-024-03361-1.

Abstract

BACKGROUND

Acute biliary pancreatitis (ABP) is a clinical common acute abdomen. After the first pancreatitis, relapse rate is high, which seriously affects human life and health and causes great economic burdens to family and society. According to a great many research findings, endoscopic retrograde cholangiopancreatography (ERCP) is an effective treatment method. However, whether ERCP should be performed in early stage of ABP is still controversial in clinical practice.

METHODS

Related articles were retrieved from Pubmed, Web of Science core library, Nature, Science Direct, and other databases published from January 2000 until now. The keywords included early ERCP, delayed ERCP, ABP, laparoscopy, and cholecystectomy, all which were connected by "or" and "and". The language of articles was not restricted during the retrieval and Review Manager5.3 was employed to perform meta-analysis of experimental data. Finally, a total of 8 eligible articles were selected, including 8,801 patients.

RESULTS

The results of the meta-analysis demonstrated that no remarkable differences were detected in the incidence of complications, mortality, and operation time between patients undergoing ERCP in early stage and those receiving delayed ERCP. However, the hospitalization time of patients in experimental group was notably shorter than that among patients in control group.

CONCLUSINS

Early ERCP treatment is as safe as late ERCP treatment for biliary pancreatitis, and can significantly shorten the hospital stay. Hence, the therapy was worthy of clinical promotion. The research findings provided reference and basis for clinical treatment of relevant diseases.

摘要

背景

急性胆源性胰腺炎(ABP)是一种常见的临床急腹症。首次胰腺炎发作后,复发率较高,严重影响人类的生命和健康,给家庭和社会带来了巨大的经济负担。大量研究表明,内镜逆行胰胆管造影(ERCP)是一种有效的治疗方法。然而,在急性胆源性胰腺炎的早期阶段是否应进行 ERCP 在临床上仍存在争议。

方法

从 Pubmed、Web of Science 核心库、Nature、Science Direct 等数据库中检索到 2000 年 1 月至今发表的相关文章。检索词包括早期 ERCP、延迟 ERCP、ABP、腹腔镜和胆囊切除术,均通过“或”和“和”连接。检索过程中不限制文章的语言,采用 Review Manager5.3 对实验数据进行荟萃分析。最终共纳入 8 篇符合标准的文献,共计 8801 例患者。

结果

荟萃分析结果表明,早期行 ERCP 与延迟行 ERCP 的患者在并发症发生率、死亡率和手术时间方面无显著差异。但实验组患者的住院时间明显短于对照组。

结论

早期 ERCP 治疗与晚期 ERCP 治疗胆源性胰腺炎同样安全,并能显著缩短住院时间。因此,该疗法值得临床推广。本研究结果为相关疾病的临床治疗提供了参考和依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3eb0/11351377/2d90b5398252/12876_2024_3361_Fig1_HTML.jpg

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