Ponphaiboon Juthaporn, Limmatvapirat Sontaya, Limmatvapirat Chutima
Department of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.
Natural Products Research Center (NPRC), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.
Foods. 2024 Aug 17;13(16):2570. doi: 10.3390/foods13162570.
This study aimed to develop a high-quality dry emulsion incorporating omega-3, 6, and 9 fatty acid-rich ostrich oil for use as a dietary supplement. Extracted from abdominal adipose tissues using a low-temperature wet rendering method, the ostrich oil exhibited antioxidant properties, favorable physicochemical properties, microbial counts, heavy metal levels, and fatty acid compositions, positioning it as a suitable candidate for an oil-in-water emulsion and subsequent formulation as a dry emulsion. Lecithin was employed as the emulsifier due to its safety and health benefits. The resulting emulsion, comprising 10% / lecithin and 10% / ostrich oil, was stable, with a droplet size of 3.93 ± 0.11 μm. This liquid emulsion underwent transformation into a dry emulsion to preserve the physicochemical stability of ostrich oil, utilizing Avicel PH-101 or Aerosil 200 through a granulation process. Although Aerosil 200 exhibited superior adsorption, Avicel PH-101 granules surpassed it in releasing the ostrich oil emulsion. Consequently, Avicel PH-101 was selected as the preferred adsorbent for formulating the ostrich oil dry emulsion. The dry emulsion, encapsulated with a disintegration time of 3.11 ± 0.14 min for ease of swallowing, maintained microbial loads and heavy metal contents within acceptable limits. Presented as granules containing butylated hydroxytoluene, the dry emulsion showcased robust temperature stability, suggesting the potential incorporation of animal fat into dry emulsions as a promising dietary supplement.
本研究旨在开发一种高品质的干乳剂，其中包含富含ω-3、6和9脂肪酸的鸵鸟油，用作膳食补充剂。鸵鸟油采用低温湿法炼制方法从腹部脂肪组织中提取，具有抗氧化性能、良好的理化性质、微生物计数、重金属含量和脂肪酸组成，使其成为水包油乳液及后续制成干乳剂的合适候选物。由于卵磷脂的安全性和健康益处，将其用作乳化剂。所得乳液含有10%的卵磷脂和10%的鸵鸟油，稳定且液滴尺寸为3.93±0.11μm。利用微晶纤维素PH-101或气相二氧化硅200通过制粒过程将这种液体乳液转化为干乳剂，以保持鸵鸟油的理化稳定性。尽管气相二氧化硅200表现出更好的吸附性，但微晶纤维素PH-101颗粒在释放鸵鸟油乳液方面超过了它。因此，微晶纤维素PH-101被选为制备鸵鸟油干乳剂的优选吸附剂。该干乳剂制成易于吞咽、崩解时间为3.11±0.14分钟的颗粒，其微生物负荷和重金属含量保持在可接受范围内。该干乳剂以含有丁基化羟基甲苯的颗粒形式呈现，具有强大的温度稳定性，表明将动物脂肪纳入干乳剂作为一种有前景的膳食补充剂具有潜力。
