Suppr超能文献

乳腺癌的风险因素及预防措施

Risk Factors and Preventive Measures for Breast Cancer.

作者信息

Winkler Marie-Christin, Hetjens Svetlana

机构信息

Department of Medical Statistics and Biomathematics, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany.

出版信息

J Clin Med. 2024 Aug 7;13(16):4610. doi: 10.3390/jcm13164610.

Abstract

Breast cancer is the most common cancer in women in many countries. Breast cancer is a multifactorial disease. This study investigates the possible influencing factors and preventive measures for breast cancer. The data for this study were obtained from WHO databases. First, age standardization was performed, followed by a correlation analysis. Relationships between the mortality rates of breast cancer and the possible influencing factors were analyzed. The significant results from the correlation analysis were analyzed using a stepwise regression analysis. In order to find out whether the application of a uniform screening program can reduce breast cancer mortality, the countries were divided into groups according to the time of initiation of the screening program, and breast cancer mortality was compared. The correlation analysis showed a significant relationship with breast cancer mortality for 15 of 30 potential influencing factors. A stepwise multivariate regression analysis was performed with these 15 factors, which revealed 13 relevant factors. Two factors were more relevant: the number of radiotherapy units per 100,000 inhabitants and the proportion of the population (over 50 years of age) with a social network. These were followed by the proportion of general practitioners and obstetricians, as well as healthcare expenses. Breast cancer mortality differed between the countries that introduced the screening program in the 1990s and those that did so in the 2020s. A country's healthcare system influences breast cancer mortality through prevention, diagnosis. and treatment. Regular screening, counseling for socially disadvantaged women, and prompt treatment are important factors. In the future, prevention measures should also aim to strengthen the social environment. The prescription of social activities should be used as preventive care.

摘要

乳腺癌是许多国家女性中最常见的癌症。乳腺癌是一种多因素疾病。本研究调查了乳腺癌可能的影响因素和预防措施。本研究的数据来自世界卫生组织数据库。首先进行年龄标准化,然后进行相关性分析。分析了乳腺癌死亡率与可能的影响因素之间的关系。使用逐步回归分析对相关性分析的显著结果进行了分析。为了确定实施统一的筛查计划是否可以降低乳腺癌死亡率,根据筛查计划启动时间将各国分为不同组,并比较了乳腺癌死亡率。相关性分析显示,30个潜在影响因素中有15个与乳腺癌死亡率存在显著关系。对这15个因素进行了逐步多元回归分析,结果显示有13个相关因素。其中两个因素更为相关:每10万居民中的放疗单位数量以及(50岁以上)拥有社交网络的人口比例。其次是全科医生和产科医生的比例以及医疗保健费用。在20世纪90年代引入筛查计划的国家和20世纪20年代引入筛查计划的国家之间,乳腺癌死亡率存在差异。一个国家的医疗保健系统通过预防、诊断和治疗影响乳腺癌死亡率。定期筛查、为社会弱势群体提供咨询以及及时治疗是重要因素。未来,预防措施还应旨在加强社会环境。应将规定社交活动作为预防性保健措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/190a/11354655/2277e3bfca37/jcm-13-04610-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验