Tsarbou Charis, Liveris Nikolaos I, Xergia Sofia A, Papageorgiou George, Kvist Joanna, Tsepis Elias
Physiotherapy Department, School of Health Rehabilitation Sciences, University of Patras, 26504 Patras, Greece.
SYSTEMA Research Centre, European University Cyprus, 2404 Nicosia, Cyprus.
J Clin Med. 2024 Aug 21;13(16):4928. doi: 10.3390/jcm13164928.
: Given the complex nature of Anterior Cruciate Ligament (ACL) injury, it is important to analyze its etiology with suitable approaches in order to formulate intervention strategies for effective prevention. The present study employs system thinking techniques to develop a Causal Loop Diagram (CLD) Model for investigating the risk factors for ACL Injury (CLD-ACLI), through a Group Model Building approach. : A two-stage procedure was applied involving a comprehensive literature review followed by several systems thinking group-modeling co-creation workshops with stakeholders. : Based on input from experts and stakeholders, combined with the latest scientific findings, the derived CLD-ACLI model revealed a series of interesting complex nonlinear interrelationships causal loops between the likelihood of ACL injury and the number of risk factors. Particularly, the interaction among institutional, psychological, neurocognitive, neuromuscular, malalignment factors, and trauma history seem to affect neuromuscular control, which subsequently may alter the biomechanics of landing, predisposing the ACL to injury. Further, according to the proposed CLD-ACLI model, the risk for injury may increase further if specific environmental and anatomical factors affect the shear forces imposed on the ACL. : The proposed CLD-ACLI model constitutes a rigorous useful conceptual presentation agreed upon among experts on the dynamic interactions among potential intrinsic and extrinsic risk factors for ACL injury. The presented causal loop model constitutes a vital step for developing a validated quantitative system dynamics simulation model for evaluating ACL injury-prevention strategies prior to implementation.
鉴于前交叉韧带(ACL)损伤的复杂性,采用合适的方法分析其病因对于制定有效的预防干预策略至关重要。本研究运用系统思维技术,通过群体模型构建方法,开发了一个因果循环图(CLD)模型,用于研究ACL损伤(CLD - ACLI)的风险因素。采用了两阶段程序,首先进行全面的文献综述,然后与利益相关者举办多次系统思维群体建模共创研讨会。基于专家和利益相关者的意见,结合最新的科学发现,得出的CLD - ACLI模型揭示了ACL损伤可能性与风险因素数量之间一系列有趣的复杂非线性相互关系因果循环。特别是,机构、心理、神经认知、神经肌肉、排列不齐因素和创伤史之间的相互作用似乎会影响神经肌肉控制,进而可能改变着陆的生物力学,使ACL易受损伤。此外,根据提出的CLD - ACLI模型,如果特定的环境和解剖因素影响施加在ACL上的剪切力,损伤风险可能会进一步增加。所提出的CLD - ACLI模型构成了一个严谨且有用的概念呈现,得到了ACL损伤潜在内在和外在风险因素之间动态相互作用方面专家的认可。所呈现的因果循环模型是在实施之前开发经过验证的定量系统动力学模拟模型以评估ACL损伤预防策略的关键一步。