Could Obesity Be Related to the Increasing Incidence of Warthin Tumors?

: The number of patients diagnosed with Warthin tumors (WTs) has increased significantly in recent years. The association of obesity as measured by body mass index (BMI) with the incidence of WTs remains unclear. This retrospective study aims to compare the BMI and other clinical factors of patients diagnosed with WTs to those with other benign epithelial parotid gland tumors. : Over a 24-year period, 465 cases of benign epithelial parotid gland tumors were treated in our department. Of these, 155 (33.3%) were diagnosed as WTs. The results of the WT group were compared with those of another benign epithelial parotid gland tumor. : The mean BMI of WT patients was 27.3, which was significantly higher than in other benign tumors (25.52; < 0.001). Furthermore, statistically significant correlations were observed, including a higher incidence of WT in males ( < 0.001), in the elderly ( < 0.001), and in cigarette smokers ( < 0.001). Additionally, a higher prevalence of other head and neck cancers was confirmed in patients with WTs ( = 0.004); : This study supports the multifactorial etiology of WT development. Among these factors, smoking, advanced age, and obesity have been identified as factors associated with the development of WT, which might be due to chronic inflammation linked to obesity.