Institute of Microbiology and Molecular Biology, Justus Liebig University Giessen, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.
Int J Mol Sci. 2024 Aug 22;25(16):9123. doi: 10.3390/ijms25169123.
is a facultative phototrophic bacterium that performs aerobic respiration when oxygen is available. Only when oxygen is present at low concentrations or absent are pigment-protein complexes formed, and anoxygenic photosynthesis generates ATP. The regulation of photosynthesis genes in response to oxygen and light has been investigated for decades, with a focus on the regulation of transcription. However, many studies have also revealed the importance of regulated mRNA processing. This study analyzes the phenotypes of wild type and mutant strains and compares global RNA-seq datasets to elucidate the impact of ribonucleases and the small non-coding RNA StsR on photosynthesis gene expression in . Most importantly, the results demonstrate that, in particular, the role of ribonuclease E in photosynthesis gene expression is strongly dependent on growth phase.
是一种兼性光合细菌，在有氧条件下进行需氧呼吸。只有在氧气浓度低或不存在时，才会形成色素-蛋白复合物，进行无氧光合作用产生 ATP。几十年来，人们一直在研究光合作用基因对氧气和光的响应调节，重点是转录调节。然而，许多研究也揭示了调节 mRNA 加工的重要性。本研究通过分析野生型和突变株的表型，并比较全局 RNA-seq 数据集，阐明了核糖核酸酶和小非编码 RNA StsR 对 中光合作用基因表达的影响。最重要的是，结果表明，特别是核糖核酸酶 E 在光合作用基因表达中的作用强烈依赖于生长阶段。
