Peride Ileana, Anastasiu Miruna, Serban Silvia Alexandra, Tiglis Mirela, Ene Razvan, Nechita Ana-Maria, Neagu Tiberiu Paul, Checherita Ionel Alexandru, Niculae Andrei
Clinical Department No. 3, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
"Marie Skłodowska Curie" Children Emergency Clinical Hospital, 077120 Bucharest, Romania.
J Pers Med. 2024 Jul 23;14(8):778. doi: 10.3390/jpm14080778.
Chronic kidney disease (CKD) represents an increasingly common pathology that affects patients' quality of life, and it is frequently associated with a high mortality rate, especially in the final stages of the disease. At the same time, diabetes mellitus is a chronic disease that contributes to the increased number of patients with CKD through diabetic kidney disease (DKD). The alternation of hypoglycemia with hyperglycemia is a condition in the occurrence of microvascular complications of diabetes, including DKD, which involves structural and functional changes in the kidneys. The therapeutic management of diabetic nephropathy is a much-discussed topic, both from nutritional medical recommendations and a pharmacotherapy perspective. The diet starting point for patients with DKD is represented by a personalized and correct adjustment of macro- and micronutrients. The importance of nutritional status in DKD patients is given by the fact that it represents a modifiable factor, which contributes to the evolution and prognosis of the disease. Since, in most cases, it is necessary to restrict many types of food, malnutrition must be considered and avoided as much as possible.
慢性肾脏病（CKD）是一种日益常见的疾病，会影响患者的生活质量，并且常常与高死亡率相关，尤其是在疾病的终末期。同时，糖尿病是一种慢性疾病，会通过糖尿病肾病（DKD）导致CKD患者数量增加。低血糖与高血糖的交替出现是糖尿病微血管并发症（包括DKD）发生过程中的一种情况，DKD涉及肾脏的结构和功能变化。从营养医学建议和药物治疗的角度来看，糖尿病肾病的治疗管理都是一个备受讨论的话题。DKD患者饮食的起点是对宏量营养素和微量营养素进行个性化且正确的调整。营养状况在DKD患者中很重要，因为它是一个可调节的因素，会影响疾病的发展和预后。由于在大多数情况下需要限制多种食物的摄入，所以必须尽可能考虑并避免营养不良。
