Parmar Uday Pratap Singh, Surico Pier Luigi, Singh Rohan Bir, Musa Mutali, Scarabosio Anna, Surico Giorgio, Maniaci Antonino, Lavalle Salvatore, D'Esposito Fabiana, Longo Antonio, Russo Andrea, Gagliano Caterina, Zeppieri Marco
Department of Ophthalmology, Government Medical College and Hospital, Chandigarh 160047, India.
Schepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.
J Pers Med. 2024 Jul 23;14(8):780. doi: 10.3390/jpm14080780.
The COVID-19 pandemic, caused by SARS-CoV-2, has significantly impacted various organ systems, including the eyes. Initially considered a primarily respiratory disease, it is now evident that COVID-19 can induce a range of ocular symptoms. Recognizing these ocular manifestations is crucial for eye care practitioners as they can serve as early indicators of the disease. This review consolidates current evidence on the ocular effects of COVID-19, identifying manifestations such as conjunctivitis, scleritis, uveitis, and retinopathy. The increasing prevalence of these symptoms highlights the importance of thorough eye examinations and detailed patient histories in COVID-19 cases. Potential routes of viral entry into ocular tissues and the underlying mechanisms, including direct infection, immune responses, and vascular involvement, are explored. Additionally, this review addresses ocular side effects associated with COVID-19 vaccines, such as corneal graft rejection, uveitis, and retinal issues. These findings emphasize the need for ongoing surveillance and research to ensure vaccine safety.
由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的2019冠状病毒病大流行对包括眼睛在内的各种器官系统产生了重大影响。COVID-19最初被认为是一种主要的呼吸道疾病，现在很明显它会引发一系列眼部症状。认识到这些眼部表现对眼科医生至关重要，因为它们可以作为该疾病的早期指标。这篇综述整合了关于COVID-19眼部影响的当前证据，确定了结膜炎、巩膜炎、葡萄膜炎和视网膜病变等表现。这些症状的日益普遍凸显了在COVID-19病例中进行全面眼部检查和详细患者病史询问的重要性。探讨了病毒进入眼组织的潜在途径及其潜在机制，包括直接感染、免疫反应和血管受累。此外，本综述还讨论了与COVID-19疫苗相关的眼部副作用，如角膜移植排斥反应、葡萄膜炎和视网膜问题。这些发现强调了持续监测和研究以确保疫苗安全的必要性。
