Mazza Marianna, Biondi-Zoccai Giuseppe, Lisci Francesco Maria, Brisi Caterina, Sfratta Greta, Rossi Sara, Traversi Gianandrea, Gaetani Eleonora, Pola Roberto, Morini Sofia, Romagnoli Enrico, Simeoni Benedetta, Covino Marcello, Marano Giuseppe
Unit of Psychiatry, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Department of Neurosciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Life (Basel). 2024 Jul 23;14(8):919. doi: 10.3390/life14080919.
Psychiatric conditions, such as depression, anxiety, bipolar disorder, and schizophrenia, are increasingly recognized as significant risk factors for cardiovascular disease (CVD). This review systematically analyzes evidence from various databases to provide a comprehensive understanding of the impact of psychiatric illnesses on the incidence, management, and prognosis of CVD. Key findings suggest a bidirectional relationship between psychiatric disorders and CVD, indicating that mental health conditions can predispose individuals to CVD, while CVD can exacerbate or trigger psychiatric symptoms. The review explores the underlying mechanisms of these associations, including behavioral factors, stress responses, and medication side effects. It also examines the challenges in managing CVD patients with comorbid psychiatric conditions, emphasizing the importance for integrated care approaches. This review underscores the necessity of considering mental health as an integral component of cardiovascular care and calls for further research to develop tailored management strategies for these complex conditions, ultimately aiming to improve patient outcomes and quality of life. This comprehensive analysis provides valuable insights for future investigations and guides clinicians in optimizing care for patients with both psychiatric and cardiovascular conditions.
诸如抑郁症、焦虑症、双相情感障碍和精神分裂症等精神疾病，日益被视为心血管疾病（CVD）的重要风险因素。本综述系统地分析了来自各种数据库的证据，以全面了解精神疾病对心血管疾病的发病率、管理和预后的影响。主要研究结果表明，精神疾病与心血管疾病之间存在双向关系，这表明心理健康状况会使个体易患心血管疾病，而心血管疾病会加重或引发精神症状。该综述探讨了这些关联的潜在机制，包括行为因素、应激反应和药物副作用。它还研究了管理患有合并精神疾病的心血管疾病患者所面临的挑战，强调了综合护理方法的重要性。本综述强调了将心理健康视为心血管护理不可或缺组成部分的必要性，并呼吁进行进一步研究，以制定针对这些复杂情况的定制管理策略，最终目标是改善患者的治疗效果和生活质量。这一全面分析为未来的研究提供了有价值的见解，并指导临床医生为患有精神疾病和心血管疾病的患者优化护理。
