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中国天然产物中生物碱的最新研究进展:结构特征和药理作用。

Recent Advances in Alkaloids from in China: Structural Characteristics and Pharmacological Effects.

机构信息

Key Laboratory of Basic and Application Research of Beiyao, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, China.

出版信息

Molecules. 2024 Aug 9;29(16):3778. doi: 10.3390/molecules29163778.

Abstract

The plant family serves as a botanical reservoir for a variety of medicinal compounds that have been traditionally utilized in Chinese medicine for numerous generations. Growing attention towards the pharmaceutical potential of has resulted in the identification of many alkaloids, which have attracted significant attention from the scientific community because of their structural complexity and wide range of biological activities, such as analgesic, antihypertensive, antiarrhythmic, anti-inflammatory, antibacterial, anti-tumor, anti-cancer, and other activities, making them potential candidates for medical use. The primary objective of this review is to analyze the existing literature on the historical use of plants, focusing on their alkaloid structures and relationship with pharmacological effects, as well as provide a theoretical basis for their clinical application, with the goal of unveiling the future potential of plants.

摘要

该植物科为各种药用化合物提供了一个植物学的资源库,这些化合物在中国医学中已经被传统使用了许多代。对 的药物潜力的日益关注导致了许多生物碱的鉴定,由于其结构复杂性和广泛的生物活性,如镇痛、降压、抗心律失常、抗炎、抗菌、抗肿瘤、抗癌等,这些生物碱引起了科学界的极大关注,使它们成为潜在的医疗用途候选物。本综述的主要目的是分析 植物的历史用途的现有文献,重点是它们的生物碱结构及其与药理作用的关系,并为它们的临床应用提供理论依据,旨在揭示 植物的未来潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e477/11357172/212cafee8d70/molecules-29-03778-g001.jpg

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