Suppr超能文献

女性正常体重肥胖的流行率及预测因素。

Prevalence and Predictors of Normal-Weight Obesity among Women.

机构信息

Department of Molecular Biology and Genetics, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.

Laboratory of Genetics of Aging and Longevity, Kazan State Medical University, 420012 Kazan, Russia.

出版信息

Nutrients. 2024 Aug 6;16(16):2579. doi: 10.3390/nu16162579.

Abstract

The present study aimed to (a) assess normal-weight obesity (NWO) and general obesity prevalence among women of different ages residing in urban areas, (b) evaluate subcutaneous fat thickness (SFT) in women with NWO, (c) establish SFT cutoff points for distinguishing NWO, and (d) explore eating habits linked to NWO. This cross-sectional study with 184 women aged 18-65 with NWO, normal weight without obesity (NWNO), overweight and general obesity included evaluation of body composition, SFT assessment using 2.5 MHz A-mode ultrasound (ISAK protocol, 7 sites) and lifestyle inquiries. The curvilinear relationship between body fat and BMI rendered BMI an unreliable indicator of adiposity in women with normal weight (BMI < 25 kg/m). Almost 30% of women with a high body fat percentage (BFP ≥ 30%) were misclassified when BMI was used to measure adiposity. The overall obesity prevalence defined by BFP was almost four times higher than that defined by BMI (56.0 vs. 18.0%, = 1 × 10). Women with NWO, overweight and general obesity shared a similar SFT profile and eating habits, setting them apart from those with NWNO. The mean SFT was the most reliable NWO predictor, with a threshold set at 12 mm equal to the 66th percentile. Mean SFT accurately classified 85% of women with NWO. While age did not significantly affect subcutaneous fat accumulation, total fat levels increased with age (R = 0.07 and R = 0.19, = 0.1 and = 9 × 10). Higher NWO prevalence in middle-aged women was linked to age-related increase in fat mass and decrease in fat-free mass. Engaging in regular physical activity and reducing snack consumption effectively countered age-related changes in body composition ( < 0.05). Women under 45 years who consumed sweet bakery items, fast food, and snacks more frequently showed higher BFP and NWO status ( < 0.05). Prevention strategies should focus on monitoring body composition and promoting healthy behaviors, particularly among young women transitioning into adulthood and women over 45 years.

摘要

本研究旨在

(a)评估不同年龄段居住在城市地区的女性中的正常体重肥胖(NWO)和一般肥胖的患病率;(b)评估 NWO 女性的皮下脂肪厚度(SFT);(c)建立区分 NWO 的 SFT 截断点;(d)探索与 NWO 相关的饮食习惯。这项横断面研究纳入了 184 名年龄在 18-65 岁之间的 NWO、正常体重非肥胖(NWNO)、超重和一般肥胖的女性,包括身体成分评估、使用 2.5 MHz A 型超声(ISAK 协议,7 个部位)评估 SFT 和生活方式调查。体脂肪与 BMI 之间的曲线关系使得 BMI 成为衡量正常体重女性(BMI<25 kg/m)体脂的不可靠指标。当 BMI 用于衡量体脂时,近 30%的体脂肪百分比高(BFP≥30%)的女性被错误分类。以 BFP 定义的总体肥胖患病率几乎是 BMI 定义的肥胖患病率的四倍(56.0%比 18.0%,=1×10)。NWO、超重和一般肥胖的女性具有相似的 SFT 特征和饮食习惯,与 NWNO 的女性不同。平均 SFT 是最可靠的 NWO 预测指标,其阈值设定为 12mm,相当于第 66 百分位数。平均 SFT 可准确分类 85%的 NWO 女性。年龄虽然对皮下脂肪积累没有显著影响,但总脂肪水平随年龄增加而增加(=0.1 和=9×10)。中年女性 NWO 患病率较高与与年龄相关的脂肪量增加和去脂体重减少有关。定期进行体育锻炼和减少零食摄入可有效对抗与年龄相关的身体成分变化(<0.05)。45 岁以下经常食用甜面包店食品、快餐和零食的女性,体脂肪率和 NWO 状况较高(<0.05)。预防策略应侧重于监测身体成分并促进健康行为,特别是在年轻女性进入成年期和 45 岁以上的女性中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dab/11357504/0671a72125df/nutrients-16-02579-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验