National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu 474-8511, Aichi, Japan.
Department of Frailty Research, Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu 474-8511, Aichi, Japan.
Nutrients. 2024 Aug 22;16(16):2800. doi: 10.3390/nu16162800.
While many studies have described the association between cognitive decline and eating habits, little attention has been paid to its association with cheese intake. In this epidemiological study of 1035 community-dwelling women aged ≥ 65, we investigated the association between intake/type of cheese and cognitive function. The anthropometry, functional ability, and the frequency of food intake, including cheese, were assessed. The mini-mental state examination (MMSE) was used to assess cognitive function, and a score of 20-26 was operationally defined as mild cognitive decline. We found that the MMSE score was significantly different between the presence of cheese intake and not (cheese intake: 28.4 ± 1.9; non-cheese intake: 27.6 ± 2.4) and between those who consumed Camembert cheese and those who did not (Camembert cheese: 28.7 ± 1.4; others: 28.3 ± 2.0). After adjusting for confounders, multiple logistic regression identified four independent variables significantly associated with mild cognitive decline: Camembert cheese intake (odds ratio = 0.448, 95% confidence interval = 0.214-0.936), age, usual walking speed, and repetitive saliva swallowing test scores. Our results, while based on cross-sectional data from Japanese community-dwelling older women, identified the significant inverse association between Camembert cheese intake and mild cognitive decline.
虽然许多研究已经描述了认知能力下降与饮食习惯之间的关联，但很少关注奶酪摄入量与认知能力下降之间的关联。在这项针对 1035 名≥65 岁社区居住女性的流行病学研究中，我们调查了奶酪摄入量/类型与认知功能之间的关系。评估了人体测量学、功能能力以及食物摄入频率，包括奶酪。采用简易精神状态检查（MMSE）评估认知功能，操作定义 20-26 分为轻度认知下降。我们发现，存在奶酪摄入与不存在奶酪摄入（奶酪摄入：28.4 ± 1.9；非奶酪摄入：27.6 ± 2.4）以及摄入卡门培尔奶酪与不摄入卡门培尔奶酪（卡门培尔奶酪：28.7 ± 1.4；其他奶酪：28.3 ± 2.0）之间的 MMSE 评分存在显著差异。在调整混杂因素后，多因素逻辑回归确定了四个与轻度认知下降显著相关的独立变量：卡门培尔奶酪摄入（比值比=0.448，95%置信区间=0.214-0.936）、年龄、常用步行速度和重复唾液吞咽测试评分。我们的结果虽然基于日本社区居住的老年女性的横断面数据，但确定了卡门培尔奶酪摄入与轻度认知下降之间存在显著的负相关关系。
