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坦桑尼亚西北部学童土壤传播蠕虫感染的患病率、感染强度及危险因素

Prevalence, Infection Intensity, and Risk Factors for Soil-transmitted Helminth Infections among School Children in Northwestern Tanzania.

作者信息

Justine Nyanda C, Bhuko Jeffer, Rubagumya Sarah L, Basinda Namanya S, Ruganuza Deodatus M, Zinga Maria M, Briet Matthieu, Misko Vyacheslav R, Legein Filip, Mohamed Hussein, Mushi Vivian, Tarimo Donath S, Mazigo Humphrey D, De Malsche Wim

机构信息

Department of Medical Parasitology and Entomology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania.

Department of Microbiology, Immunology and Parasitology, St. Joseph College of Health and Allied Sciences, St. Joseph University in Tanzania, Dar es Salaam P.O. Box 11007, Tanzania.

出版信息

Pathogens. 2024 Jul 27;13(8):627. doi: 10.3390/pathogens13080627.

Abstract

Soil-transmitted helminthiases (STH) are among the neglected tropical diseases and infect more than 24% of the world population. The World Health Organization recommends regular monitoring of STH's prevalence and intensity following mass drug administrations to evaluate their effectiveness and inform future control strategies. This study evaluated the prevalence, intensity, and risk factors of STH infections among school children aged 6 to 14 years old in northwestern Tanzania. A cross-sectional study was conducted among 728 school children in the Kagera region in 2021. Participants were selected using a two-stage cluster sampling method. A questionnaire was used to collect data on the risk factors. Stool samples were examined using the Kato-Katz technique. The data were analysed using STATA. The overall prevalence of STH was 56.2% (95% CI: 52.5-59.8, 409/728). About 5.7% and 1.1% of the infected children had moderate-intensity infections with and respectively. Risk factors included the mother's occupation as a farmer (aOR: 1.2, = 0.002) and not washing hands with water and soap (aOR: 1.4, = 0.035). Washing one's hands after using the toilet (aOR: 0.6; = 0.024) is a preventive measure against STH infections. STH was prevalent in the study area. The mother's occupation (farmer) and the lack of handwashing with water and soap influenced STH transmission. Conversely, washing hands after visiting the toilet and after playing with soil reduced the risk of STH infection.

摘要

土壤传播的蠕虫病(STH)属于被忽视的热带病,感染了全球超过24%的人口。世界卫生组织建议在大规模药物给药后定期监测STH的流行率和感染强度,以评估其有效性并为未来的控制策略提供依据。本研究评估了坦桑尼亚西北部6至14岁学童中STH感染的流行率、感染强度及危险因素。2021年在卡盖拉地区的728名学童中开展了一项横断面研究。采用两阶段整群抽样方法选取参与者。使用问卷收集危险因素的数据。粪便样本采用加藤厚涂片法进行检测。数据使用STATA进行分析。STH的总体流行率为56.2%(95%CI:52.5 - 59.8,409/728)。分别约有5.7%和1.1%的感染儿童患有中度强度的 和 感染。危险因素包括母亲的职业为农民(调整后比值比:1.2,P = 0.002)以及未用肥皂和水洗手(调整后比值比:1.4,P = 0.035)。便后洗手(调整后比值比:0.6;P = 0.024)是预防STH感染的一项措施。STH在研究地区流行。母亲的职业(农民)以及缺乏用肥皂和水洗手影响了STH的传播。相反,便后洗手以及在玩土后洗手可降低STH感染风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3204/11357449/d86a65aa871b/pathogens-13-00627-g001.jpg

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