Department of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Cephalalgia. 2024 Aug;44(8):3331024241274266. doi: 10.1177/03331024241274266.
The present study aimed to assess the burden of neck pain in adults with migraine and tension-type headache (TTH), utilizing the Neck Disability Index (NDI) and Numeric Pain Rating Scale (NPRS).
A systematic literature search was conducted on PubMed and Embase to identify observational studies assessing NDI and NPRS in populations with migraine or TTH. The screening of articles was independently performed by two investigators (HMA and ZA). Pooled mean estimates were calculated through random-effects meta-analysis. The statistic assessed between-study heterogeneity, and meta-regression further explored heterogeneity factors.
Thirty-three clinic-based studies met the inclusion criteria. For participants with migraine, the pooled mean NDI score was 16.2 (95% confidence interval (CI) = 13.2-19.2, = 99%). Additionally, the mean NDI was 5.5 (95% CI = 4.11-6.8, < 0.001) scores higher in participants with chronic compared to episodic migraine. The pooled mean NDI score for participants with TTH was 13.7 (95% CI = 4.9-22.4, = 99%). In addition, the meta-analysis revealed a mean NPRS score of 5.7 (95% CI = 5.1-6.2, = 95%) across all participants with migraine.
This systematic review and meta-analysis shows a greater degree of neck pain-related disability in migraine compared to TTH. Nevertheless, the generalizability of these findings is constrained by methodological variations identified in the current literature.
本研究旨在利用颈部残疾指数（NDI）和数字疼痛评分量表（NPRS）评估偏头痛和紧张型头痛（TTH）成人的颈部疼痛负担。
对 PubMed 和 Embase 进行系统文献检索，以确定评估偏头痛或 TTH 人群中 NDI 和 NPRS 的观察性研究。两名研究人员（HMA 和 ZA）独立进行文章筛选。通过随机效应荟萃分析计算汇总均值估计值。Q 统计量评估研究间异质性，荟萃回归进一步探索异质性因素。
33 项基于诊所的研究符合纳入标准。对于偏头痛患者，汇总平均 NDI 评分为 16.2（95%置信区间[CI]：13.2-19.2，=99%）。此外，与发作性偏头痛相比，慢性偏头痛患者的平均 NDI 评分高 5.5（95%CI：4.11-6.8， < 0.001）。TTH 患者的汇总平均 NDI 评分为 13.7（95%CI：4.9-22.4，=99%）。此外，荟萃分析显示所有偏头痛患者的平均 NPRS 评分为 5.7（95%CI：5.1-6.2，=95%）。
本系统评价和荟萃分析显示，偏头痛患者的颈部疼痛相关残疾程度高于 TTH。然而，这些发现的普遍性受到当前文献中确定的方法学差异的限制。
