Department of Biomedical Sciences, University of Gadarif, Gadarif, Sudan.
Department of Veterinary Surgery, AL-Salam University, West Kordofan, Sudan.
Vet Q. 2024 Dec;44(1):1-18. doi: 10.1080/01652176.2024.2396577. Epub 2024 Aug 29.
, a ubiquitous zoonotic parasite infecting warm-blooded animals, poses a significant health threat to workers with occupational animal exposure (WOEA) due to their frequent contact with potential reservoirs. Existing data on seroprevalence in the WOEA exhibits substantial global variation. This systematic review and meta-analysis, adhering to PRISMA guidelines, aimed to quantify the global seroprevalence of infection among WOEA over the past five decades (1972-2023). We identified 66 eligible studies through a comprehensive search strategy encompassing English publications, with a total sample size of 15,279. A random-effects model with the Freeman-Tukey transformation in STATA v16.0 accounted for the high heterogeneity observed. We estimated the pooled global seroprevalence of infection in WOEA at 41% (95% CI: 36-47%). Subgroup analyses revealed significant variations by gender: males (63%) vs. females (37%) ( < 0.05), occupation: non-livestock workers (54%), livestock workers (47%), slaughterhouse workers (44%), and veterinary personnel (27%) ( < 0.05). Geographic trends showed the highest prevalence in Africa (51%), followed by South America (49%), Europe (47%), Australia (43%), Asia (36%), and North America (23%; < 0.05). Lower prevalence was observed in high-income (39%) and upper-middle-income (38%) countries compared to lower-middle-income (44%) and low-income (48%) countries ( < 0.05). This analysis underscores the high global seroprevalence of in the WOEA, highlighting the need for targeted interventions in this high-risk population.
旋毛虫是一种普遍存在的人畜共患寄生虫，感染温血动物，由于职业性动物接触（WOEA）的工人经常接触潜在的宿主，因此对他们的健康构成重大威胁。WOEA 中 感染的血清阳性率存在很大的全球差异。本系统评价和荟萃分析遵循 PRISMA 指南，旨在量化过去五十年（1972-2023 年）WOEA 中 感染的全球血清阳性率。我们通过一项全面的搜索策略，包括英语出版物，共识别出 66 项符合条件的研究，总样本量为 15279 人。STATA v16.0 中的随机效应模型和 Freeman-Tukey 变换用于解释观察到的高度异质性。我们估计 WOEA 中 感染的全球血清阳性率为 41%（95%CI：36-47%）。亚组分析显示，性别（男性 63%，女性 37%）和职业（非畜牧业工人 54%，畜牧业工人 47%，屠宰场工人 44%，兽医人员 27%）差异有统计学意义（ < 0.05）。地理趋势显示，非洲的患病率最高（51%），其次是南美洲（49%）、欧洲（47%）、澳大利亚（43%）、亚洲（36%）和北美洲（23%）（ < 0.05）。与中低收入（44%）和低收入（48%）国家相比，高收入（39%）和中上收入（38%）国家的患病率较低（ < 0.05）。这项分析强调了 WOEA 中 感染的高全球血清阳性率，突出了在这一高危人群中需要进行有针对性的干预。
