Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Department of Parasitology, Sari Medical School, Mazandaran University of Medical Sciences, Sari, Iran.
Parasit Vectors. 2020 Feb 17;13(1):82. doi: 10.1186/s13071-020-3954-1.
Felids (domestic and wild cats) are important in the epidemiology of the parasite Toxoplasma gondii because they are the only hosts that can excrete the environmentally resistant oocysts. We conducted a systematic review and meta-analysis to estimate the global prevalence of T. gondii in species of the family Felidae.
We searched seven databases (PubMed, Embase, Google Scholar, ScienceDirect, Scopus, Proquest and Web of Science) for studies reporting seroprevalence of T. gondii in felids from 1967 to 31 December 2017. A total of 217 published papers, containing 223 datasets were eligible for inclusion in the meta-analysis, comprised 59,517 domestic and 2733 wild cats from 1967 to 2017.
The pooled global T. gondii seroprevalence was estimated to be 35% (95% CI: 32-38%) and 59% (95% CI: 56-63%) in domestic cats and wild felids, respectively, using random effects model. The seroprevalence was higher in Australia and Africa where the T. gondii seropositivity in domestic cats was 52% (95% CI: 15-89%) and 51% (95% CI: 20-81%), respectively. The lowest seroprevalence was estimated in Asia 27% (95% CI: 24-30%). The seroprevalence values for T. gondii in wild felids were 74% (95% CI: 62-83%) in Africa, 67% (95% CI: 23-111%) in Asia, 67% (95% CI: 58-75%) in Europe and 66% (95% CI: 41-91%) in South America.
Our study provides the global prevalence of T. gondii in species of the family Felidae and is a source of information to aid public health workers in developing prevention plans.
猫科动物（家猫和野生猫科动物）在寄生虫刚地弓形虫的流行病学中很重要，因为它们是唯一能够排出环境中具有抗性的卵囊的宿主。我们进行了一项系统综述和荟萃分析，以估计猫科动物中刚地弓形虫的全球流行率。
我们检索了七个数据库（PubMed、Embase、Google Scholar、ScienceDirect、Scopus、Proquest 和 Web of Science），以查找 1967 年至 2017 年 12 月 31 日期间报道猫科动物刚地弓形虫血清流行率的研究。共有 217 篇已发表的论文，其中包含 223 个数据集，符合纳入荟萃分析的条件，包括 1967 年至 2017 年期间的 59517 只家猫和 2733 只野生猫。
使用随机效应模型，估计全球范围内家猫和野生猫科动物的刚地弓形虫总血清流行率分别为 35%（95%CI：32-38%）和 59%（95%CI：56-63%）。在澳大利亚和非洲，家猫的刚地弓形虫血清阳性率分别为 52%（95%CI：15-89%）和 51%（95%CI：20-81%），血清流行率较高。在亚洲，估计的血清流行率最低，为 27%（95%CI：24-30%）。在非洲，野生猫科动物的刚地弓形虫血清流行率为 74%（95%CI：62-83%），在亚洲为 67%（95%CI：23-111%），在欧洲为 67%（95%CI：58-75%），在南美洲为 66%（95%CI：41-91%）。
本研究提供了猫科动物中刚地弓形虫的全球流行率，为公共卫生工作者制定预防计划提供了信息来源。
