Al-Obudi Yasser, Khurram Ruhaid, Bhogal Palveer, Nawab Hasan, Bell James
Department of Radiology, The Royal Free Hospital, NHS Foundation Trust, London, United Kingdom.
Radiol Case Rep. 2024 Aug 5;19(10):4554-4560. doi: 10.1016/j.radcr.2024.07.032. eCollection 2024 Oct.
Neuroendocrine tumors are malignant neoplasms arising from neuroendocrine cells. These are increasingly recognized with rising incidence and encompass a diverse range of phenotypes. The large majority of these originate in the gastrointestinal tract however primary neuroendocrine tumors have also been reported to arise in a variety of organs such as lung, breast, prostate, and skin. Primary malignant paratesticular masses are often sarcomatous in origin and metastatic spread to the paratesticular region or scrotum is exceedingly rare. We report a fascinating case of a 56-year-old male who had an unusual initial presentation of paratesticular lesions on a background of an undescended testicle and an incidental umbilical nodule. After a combination of radiological and histopathological investigations, he was diagnosed with metastatic midgut neuroendocrine tumor.
神经内分泌肿瘤是起源于神经内分泌细胞的恶性肿瘤。随着发病率的上升,这些肿瘤越来越受到认可,并且涵盖了多种不同的表型。其中绝大多数起源于胃肠道,然而也有报道称原发性神经内分泌肿瘤可发生于多种器官,如肺、乳腺、前列腺和皮肤。原发性睾丸旁恶性肿块通常起源于肉瘤,转移至睾丸旁区域或阴囊极为罕见。我们报告了一例令人着迷的病例,一名56岁男性,在隐睾和偶然发现的脐部结节背景下,出现了不寻常的睾丸旁病变初始表现。经过影像学和组织病理学检查相结合,他被诊断为转移性中肠神经内分泌肿瘤。