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鞣酸和二苯甲酮对大豆脂氧合酶和公羊精囊环氧化酶的抑制作用。

Inhibitory effects of tannic acid and benzophenone on soybean lipoxygenase and ram seminal vesicle cyclooxygenase.

作者信息

Goswami S K, Kinsella J E

出版信息

Prostaglandins Leukot Med. 1985 Feb;17(2):223-8. doi: 10.1016/0262-1746(85)90109-x.

DOI:10.1016/0262-1746(85)90109-x
PMID:3920681
Abstract

Soybean lipoxygenase and cyclooxygenase from ram seminal vesicles were inhibited by tannic acid and the apparent ID50's were 7.5 x 10(-7) M and 6 x 10(-6) M, respectively. The inhibition of lipoxygenase by tannic acid was noncompetitive. Benzophenone inhibited cyclooxygenase, and the ID50 was 8 x 10(-7) M. The inhibition constant, Ki values of both tannic acid and benzophenone are presented.

摘要

来自公羊精囊的大豆脂氧合酶和环氧化酶受到单宁酸的抑制,其表观半数抑制浓度(ID50)分别为7.5×10⁻⁷ M和6×10⁻⁶ M。单宁酸对脂氧合酶的抑制作用是非竞争性的。二苯甲酮抑制环氧化酶,其半数抑制浓度(ID50)为8×10⁻⁷ M。文中给出了单宁酸和二苯甲酮的抑制常数(Ki值)。

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