Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine, Deakin University, Barwon Health, Geelong, Victoria, Australia; email:
Research Institute for Future Health, Gold Coast, Queensland, Australia.
Annu Rev Nutr. 2024 Aug;44(1):383-404. doi: 10.1146/annurev-nutr-062322-020650.
Our aim was to conduct an umbrella review of evidence from meta-analyses of observational studies investigating the link between sugar-sweetened beverage consumption and human health outcomes. Using predefined evidence classification criteria, we evaluated evidence from 47 meta-analyses encompassing 22,055,269 individuals. Overall, 79% of these analyses indicated direct associations between greater sugar-sweetened beverage consumption and higher risks of adverse health outcomes. Convincing evidence (class I) supported direct associations between sugar-sweetened beverage consumption and risks of depression, cardiovascular disease, nephrolithiasis, type 2 diabetes mellitus, and higher uric acid concentrations. Highly suggestive evidence (class II) supported associations with risks of nonalcoholic fatty liver disease and dental caries. Out of the remaining 40 meta-analyses, 29 were graded as suggestive or weak in the strength of evidence (classes III and IV), and 11 showed no evidence (class V). These findings inform and provide support for population-based and public health strategies aimed at reducing sugary drink consumption for improved health.
我们的目的是对观察性研究荟萃分析的证据进行伞式审查，这些研究调查了糖饮料消费与人类健康结果之间的联系。使用预先确定的证据分类标准，我们评估了涵盖 22055269 人的 47 项荟萃分析的证据。总体而言，这些分析中有 79%表明糖饮料消费与不良健康结果的风险之间存在直接关联。令人信服的证据（I 类）支持糖饮料消费与抑郁、心血管疾病、肾结石、2 型糖尿病和尿酸浓度升高风险之间的直接关联。高度提示性证据（II 类）支持与非酒精性脂肪肝疾病和龋齿风险的关联。在其余的 40 项荟萃分析中，29 项的证据强度被评为提示性或弱（III 类和 IV 类），11 项则没有证据（V 类）。这些发现为基于人群和公共卫生策略提供了信息和支持，旨在减少含糖饮料的消费，以改善健康。
