Ofosu F A, Blajchman M A, Kaegi A, Turc J M
Vox Sang. 1985;48(4):213-6. doi: 10.1111/j.1423-0410.1985.tb00174.x.
The storage of fresh frozen plasma (FFP) for short periods at -20 degrees C for 6 weeks, -30 degrees C for 12 weeks, or -40 degrees C for 12 weeks, did not result in significant deterioration in factor VIII: coagulant (factor VIII:C) activity in the primary packs. In studies examining whether plasma segments could be used for quality control purposes, the mean factor VIII:C activity of the primary pack was found to be identical to that of the attached segments of plasma for units of FFP which were thawed within 2 h after preparation. This was also true for FFP units stored at -40 and -60 degrees C for up to 12 weeks. There was, however, a loss in factor VIII:C activity in the segments of FFP units stored at either -20 or -30 degrees C for 6 and 12 weeks, respectively. Thus for units of FFP stored at temperatures colder than -40 degrees C, segments are suitable for assessing the factor VIII:C activity in the primary pack but not for FFP units stored at -20 or -30 degrees C.
新鲜冰冻血浆（FFP）在-20℃短期储存6周、-30℃储存12周或-40℃储存12周，其主袋中凝血因子VIII：促凝剂（因子VIII：C）活性未出现显著下降。在研究血浆段是否可用于质量控制目的时，发现对于制备后2小时内解冻的FFP单位，主袋的平均因子VIII：C活性与所附血浆段的相同。对于在-40℃和-60℃储存长达12周的FFP单位也是如此。然而，分别在-20℃或-30℃储存6周和12周的FFP单位的血浆段中，因子VIII：C活性有所损失。因此，对于储存在低于-40℃温度下的FFP单位，血浆段适用于评估主袋中的因子VIII：C活性，但不适用于储存在-20℃或-30℃的FFP单位。
