Plotz R D, Ciotola R T
Department of Pathology, Brown University, Providence, Rhode Island.
Am J Clin Pathol. 1988 Mar;89(3):381-4. doi: 10.1093/ajcp/89.3.381.
Packs of fresh-frozen plasma (FFP) from the same donor units were thawed at 37 degrees C and at 45 degrees C in order to determine the suitability of the higher temperature for thawing FFP. Measurements of prothrombin time, activated partial thromboplastin time, fibrinogen concentration, and Factor VIII activity showed no significant differences between the temperatures. Thawing time at 45 degrees C was approximately half that at 37 degrees C. The protocol for manipulation and inspection of the FFP was an important determinant of the thawing time, but did not appear to affect coagulation. FFP can safely be thawed in a 45 degrees C water bath if it is removed before thawing is complete.
为了确定较高温度解冻新鲜冰冻血浆（FFP）的适用性，将来自相同供体单位的FFP包装分别在37℃和45℃解冻。凝血酶原时间、活化部分凝血活酶时间、纤维蛋白原浓度和因子VIII活性的测量结果显示，不同温度之间无显著差异。45℃的解冻时间约为37℃的一半。FFP的操作和检查规程是解冻时间的重要决定因素，但似乎不影响凝血功能。如果在解冻完成前取出，FFP可以在45℃水浴中安全解冻。
