Oh Juyeon, Chung Eun Joo, Jung Jin Ho, Lee Jin San, Oh Seong-Il
College of Nursing, Dankook University, Cheonan, Republic of Korea.
Department of Neurology, Busan Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.
Eur Neurol. 2024;87(5-6):230-241. doi: 10.1159/000541172. Epub 2024 Aug 29.
Long COVID can also lead to neurological sequelae that affect existing diseases. This study explored how COVID-19 infection affects neurological patients and the relationship between long COVID and exacerbating factors.
This retrospective study was conducted on 85 patients with neurological diseases after COVID-19 at the Neurology Department, Inje University Busan Paik Hospital, Korea. The data were collected between August and October 2022. The patients had a medical history, including COVID-19 infection, and completed symptom questionnaires. A long COVID questionnaire consisting of 35 inquiries in 10 categories was completed. Anxiety, depression, fatigue, functional difficulties, QOL, and health status changes were assessed.
The analysis comprised 85 participants (age: 56.4 ± 15.2 years; 63.5% women). Of the categories, neurological symptoms (68.2%) were the most prevalent, followed by systemic symptoms (64.7%) and cardiopulmonary symptoms (56.5%). Anxiety, depression, and fatigue symptoms were reported by 36.5%, 34.1%, and 42.4% of the participants. Subjective neurological deterioration after COVID-19 was reported in 28 participants (28/81, 34.6%). Anxiety, depression, and fatigue were influenced by long COVID symptoms and the subjective deterioration of neurological conditions.
This study analyzed the long COVID symptoms in patients with preexisting neurological conditions and their impact on mental health and quality of life. One-third of the participants reported a subjective worsening of their preexisting neurological conditions. This study highlights the need for comprehensive follow-ups and a multidisciplinary approach for patients with neurological conditions and prolonged COVID-19 symptoms.
新冠后长期症状（Long COVID）也可导致影响现有疾病的神经后遗症。本研究探讨了新冠病毒感染如何影响神经系统疾病患者以及Long COVID与加重因素之间的关系。
本回顾性研究对韩国仁济大学釜山白医院神经内科85例新冠后神经系统疾病患者进行。数据收集于2022年8月至10月期间。患者有包括新冠病毒感染在内的病史，并完成了症状问卷。完成了一份包含10个类别35项询问的Long COVID问卷。评估了焦虑、抑郁、疲劳、功能困难、生活质量（QOL）和健康状况变化。
分析包括85名参与者（年龄：56.4±15.2岁；63.5%为女性）。在这些类别中，神经症状（68.2%）最为普遍，其次是全身症状（64.7%）和心肺症状（56.5%）。36.5%、34.1%和42.4%的参与者报告有焦虑、抑郁和疲劳症状。28名参与者（28/81，34.6%）报告新冠后主观神经功能恶化。焦虑、抑郁和疲劳受Long COVID症状和神经状况主观恶化的影响。
本研究分析了患有既往神经系统疾病患者的Long COVID症状及其对心理健康和生活质量的影响。三分之一的参与者报告其既往神经系统疾病主观恶化。本研究强调了对患有神经系统疾病和新冠长期症状患者进行全面随访和多学科方法的必要性。
