Division of Health Systems and Public Health, Department of Global Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa
Country Readiness and Strengthening Department, World Health Emergencies Programme, World Health Organization, Geneva, Switzerland.
BMJ Glob Health. 2024 Aug 29;9(8):e014379. doi: 10.1136/bmjgh-2023-014379.
COVID-19 showed that countries must strengthen their operational readiness (OPR) capabilities to respond to an imminent pandemic threat rapidly and proactively. We conducted a rapid scoping evidence review to understand the definition and critical elements of OPR against five core sub-systems of a new framework to strengthen the global architecture for Health Emergency Preparedness Response and Resilience (HEPR).
We searched MEDLINE, Embase, and Web of Science, targeted repositories, websites, and grey literature databases for publications between 1 January 2010 and 29 September 2021 in English, German, French or Afrikaans. Included sources were of any study design, reporting OPR, defined as immediate actions taken in the presence of an imminent threat, from groups who led or responded to a specified health emergency. We used prespecified and tested methods to screen and select sources, extract data, assess credibility and analyse results against the HEPR framework.
Of 7005 sources reviewed, 79 met the eligibility criteria, including 54 peer-reviewed publications. The majority were descriptive reports (28%) and qualitative analyses (30%) from early stages of the COVID-19 pandemic. Definitions of OPR varied while nine articles explicitly used the term 'readiness', others classified OPR as part of preparedness or response. Applying our working OPR definition across all sources, we identified OPR actions within all five HEPR subsystems. These included resource prepositioning for early detection, data sharing, tailored communication and interventions, augmented staffing, timely supply procurement, availability and strategic dissemination of medical countermeasures, leadership, comprehensive risk assessment and resource allocation supported by relevant legislation. We identified gaps related to OPR for research and technology-enabled manufacturing platforms.
OPR is in an early stage of adoption. Establishing a consistent and explicit framework for OPRs within the context of existing global legal and policy frameworks can foster coherence and guide evidence-based policy and practice improvements in health emergency management.
COVID-19 表明,各国必须加强运营准备能力(OPR),以便迅速、积极地应对迫在眉睫的大流行威胁。我们进行了快速范围界定证据审查,以了解针对新框架的五个核心子系统加强全球卫生应急准备和恢复能力(HEPR)的全球架构的 OPR 的定义和关键要素。
我们在 2010 年 1 月 1 日至 2021 年 9 月 29 日期间,以英文、德文、法文或南非荷兰文在 MEDLINE、Embase 和 Web of Science、目标存储库、网站和灰色文献数据库中搜索了有关 OPR 的出版物,包括任何研究设计,将 OPR 定义为在迫在眉睫的威胁存在时立即采取的行动,这些来源来自领导或应对特定卫生紧急情况的团体。我们使用了预设和经过测试的方法来筛选和选择来源、提取数据、评估可信度,并根据 HEPR 框架分析结果。
在审查的 7005 个来源中,有 79 个符合资格标准,包括 54 篇同行评议出版物。其中大部分是 COVID-19 大流行早期的描述性报告(28%)和定性分析(30%)。OPR 的定义各不相同,而有 9 篇文章明确使用了“准备”一词,其他文章则将 OPR 归类为准备或应对的一部分。将我们的工作 OPR 定义应用于所有来源,我们在所有五个 HEPR 子系统中都确定了 OPR 行动。其中包括早期检测的资源前置、数据共享、量身定制的沟通和干预措施、增加人员配备、及时采购供应品、医疗对策的可用性和战略传播、领导能力、全面风险评估和相关立法支持的资源分配。我们发现与研究和技术驱动的制造平台的 OPR 相关的差距。
OPR 处于早期采用阶段。在现有全球法律和政策框架的背景下,为 OPR 建立一个一致和明确的框架,可以促进一致性,并指导卫生应急管理方面基于证据的政策和实践改进。