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婴儿先天性纵隔肿块的麻醉:病例报告。

Anesthesia for an infant with congenital mediastinal mass: a case report.

机构信息

Pediatric Anesthesia Section, Department of General Anesthesia, Anesthesiology and Perioperative Medicine Administration, King Fahad Medical City, Second Health Cluster, Riyadh, Saudi Arabia.

出版信息

J Med Case Rep. 2024 Aug 30;18(1):412. doi: 10.1186/s13256-024-04677-y.

Abstract

BACKGROUND

Giant anterior mediastinal masses in infants are one of the most challenging cases faced in pediatric anesthesia practice. They can pose unique challenges for resection such as cardiovascular collapse on induction of anesthesia and injury to surrounding structures that maybe compressed or displaced. Principles that must be followed and kept in mind during removal of giant mediastinal mass include appropriate diagnostic imaging to define mass extent, airway control during induction, a multidisciplinary team approach including cardiothoracic for sternotomy, cannulation to institute cardiopulmonary bypass, otolaryngology for rigid bronchoscopy, preservation of neurovascular structure, and complete resection whenever possible. Our patient had a mass that weighed twice his whole body weight.

CASE PRESENTATION

Here we present a 3-month-old Middle Eastern infant weighing 3.2 kg with a large congenital teratoma who presented to the emergency room with cyanosis and respiratory distress. During his hospital course, he underwent three procedures, two of them under light-to-moderate sedation: a diagnostic computer tomography scan followed by mass content drainage by interventional radiology (Figs. 1, 2). On the third day, he had a thoracotomy with complete tumor resection under general anesthesia with the help of an epidural for pain control (Fig. 3). The resected tumor weighed 2.5 kg, which was equal to twice the patient's total body weight (Fig. 4). After the surgery, he was extubated in the operating room and discharged home 3 days later. Fig. 1 Anterior-posterior chest x-ray showing the anterior mediastinal mass (AMM) Fig. 2 Cross-section computed tomography (CT) showing large anterior mediastinal mass (AMM) Fig. 3 Gross anatomy of the tumor before resection Fig. 4 Gross anatomy of the removed tumor CONCLUSION: Anterior mediastinal mass patients can be challenging for the anesthesiologist. They need meticulous thorough perioperative assessment to determine the extent of compression on major intramediastinal structures and to predict the complications. Planning by multidisciplinary team and discussion with the family is important. These types of cases should be preferably operated on by an experienced team in a well-equipped operation room in tertiary care institutes.

摘要

背景

婴儿巨大前纵隔肿块是小儿麻醉实践中最具挑战性的病例之一。它们在切除时可能会带来独特的挑战,例如麻醉诱导时心血管崩溃和周围结构受压或移位导致的损伤。切除巨大纵隔肿块时必须遵循和牢记的原则包括进行适当的诊断成像以确定肿块范围、诱导时的气道控制、包括心胸外科医生进行胸骨切开术、进行心内直视术以建立体外循环、耳鼻喉科医生进行硬式支气管镜检查、保护神经血管结构以及尽可能进行完全切除。我们的患者有一个重达他全身两倍的肿块。

病例介绍

这里我们介绍一个 3 个月大的中东婴儿,体重 3.2 公斤,患有大型先天性畸胎瘤,因发绀和呼吸窘迫急诊入院。在他的住院期间,他接受了三次手术,其中两次在轻度至中度镇静下进行:一次诊断性计算机断层扫描,然后由介入放射学进行肿块内容物引流(图 1、2)。第三天,他在全身麻醉下进行了开胸手术,在硬膜外麻醉的帮助下进行疼痛控制(图 3)。切除的肿瘤重 2.5 公斤,相当于患者体重的两倍(图 4)。手术后,他在手术室拔管,3 天后出院回家。

图 1 前后位胸部 X 射线显示前纵隔肿块(AMM)

图 2 横断位计算机断层扫描(CT)显示大型前纵隔肿块(AMM)

图 3 肿瘤切除前的大体解剖

图 4 切除的肿瘤的大体解剖

结论

前纵隔肿块患者对麻醉医生来说可能具有挑战性。他们需要进行细致彻底的围手术期评估,以确定对主要纵隔内结构的压迫程度,并预测并发症。多学科团队的规划和与家属的讨论很重要。这类病例最好由经验丰富的团队在三级保健机构的设备齐全的手术室进行操作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd6/11363491/588d1f1aa3fb/13256_2024_4677_Fig1_HTML.jpg

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