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对在随机对照试验招募过程中使用技术的利弊进行的定性探索。

A qualitative exploration of advantages and disadvantages to using technology in the process of randomised controlled trial recruitment.

作者信息

Muldowney Lauren A, Hynes Sinéad M, Oglesby Megan, Dwyer Christopher P

机构信息

School of Medicine, University of Galway, Galway, County Galway, Ireland.

Occupational Therapy, School of Health Sciences, University of Galway, Galway, County Galway, Ireland.

出版信息

HRB Open Res. 2024 Jun 6;6:56. doi: 10.12688/hrbopenres.13776.2. eCollection 2023.

Abstract

BACKGROUND

Despite its importance, recruiting a sufficient sample size for randomised controlled trials (RCTs) can pose a significant challenge, which has real-world impact on reliability of evidence, trial completion and ultimately, patient care. Technology has potential to enhance the recruitment process, but there is a lack of evidence regarding its current use and effectiveness. Consistent with findings from the PRioRiTy I study, the current research aims to explore the advantages and disadvantages to using technology during the recruitment process for RCTs.

METHODS

Semi-structured interviews (n=7) were conducted with researchers involved in RCT recruitment in Ireland. Subsequently, a Public & Patient Involvement (PPI) panel focus group (n=3) was conducted to add further depth to these findings. The data were qualitatively analysed through 'Reflexive Thematic Analysis' to extract prominent themes.

RESULTS

A superordinate theme arose: , along with two themes, which were corroborated by the PPI focus group: and

CONCLUSIONS

This study provided a deeper understanding of the factors which influence researchers to employ technology in recruitment for RCTs. Implications suggest that future researchers should aim to adapt their recruitment approaches to meet digital tool preferences of their target cohort; and engage with patient groups in the community to allow networking opportunities for future studies. This research may contribute towards maximising efficiency in RCT recruitment.

摘要

背景

尽管随机对照试验(RCT)招募足够的样本量很重要,但这可能带来重大挑战,对证据的可靠性、试验完成情况以及最终的患者护理都有实际影响。技术有潜力加强招募过程,但缺乏关于其当前使用情况和有效性的证据。与PRioRiTy I研究的结果一致,当前研究旨在探讨在RCT招募过程中使用技术的优缺点。

方法

对参与爱尔兰RCT招募的研究人员进行了半结构化访谈(n = 7)。随后,开展了一个公众与患者参与(PPI)小组焦点小组(n = 3),以进一步深化这些发现。通过“反思性主题分析”对数据进行定性分析,以提取突出主题。

结果

出现了一个上级主题,以及两个主题,这些主题得到了PPI焦点小组的证实: 和

结论

本研究更深入地了解了影响研究人员在RCT招募中使用技术的因素。研究结果表明,未来的研究人员应旨在调整其招募方法,以满足目标人群对数字工具的偏好;并与社区中的患者群体合作,为未来的研究提供建立联系的机会。这项研究可能有助于提高RCT招募的效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36e/11358755/6f2da23735b7/hrbopenres-6-15257-g0000.jpg

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