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化脓性甲状腺炎:一名免疫功能低下患者并发诺卡菌属和结核分枝杆菌感染

Suppurative Thyroiditis: Coinfection by Nocardia spp. and Mycobacterium tuberculosis in an Immunocompromised Patient.

作者信息

Garcia Rueda Jhon Edwar, Monsalve Naranjo Andrés David, Giraldo Benítez Carolina, Ramírez Quintero Juan David

机构信息

Internal Medicine, Pontifical Bolivarian University, Medellin, COL.

Internal Medicine, Pablo Tobon Uribe Hospital, Medellin, COL.

出版信息

Cureus. 2024 Jul 30;16(7):e65744. doi: 10.7759/cureus.65744. eCollection 2024 Jul.

Abstract

Suppurative thyroiditis is a rare entity with a low incidence in thyroid diseases, manifesting with pain, fever, dysphagia, and dysphonia. Its infrequency is explained by the thyroid gland's resistance to infections due to its encapsulated position, high blood flow, bactericidal action of iodine, and extensive lymphatic network. We present the first report in the literature of a 72-year-old woman with a history of inflammatory myopathy and immunosuppression diagnosed with suppurative thyroiditis co-infected with Nocardia spp. and Mycobacterium tuberculosis. This entity requires a high clinical suspicion, and fine-needle aspiration biopsy (FNAB) is preferred as the diagnostic method for microbiological sampling. Although rare, it carries high morbidity and mortality if not suspected in time.

摘要

化脓性甲状腺炎是一种在甲状腺疾病中发病率较低的罕见病症,表现为疼痛、发热、吞咽困难和声音嘶哑。其发病率低的原因在于甲状腺由于其被膜包裹的位置、高血流量、碘的杀菌作用以及广泛的淋巴网络而对感染具有抵抗力。我们报告了文献中首例患有炎性肌病和免疫抑制病史的72岁女性,诊断为化脓性甲状腺炎合并诺卡菌属和结核分枝杆菌感染。该病症需要高度的临床怀疑,细针穿刺活检(FNAB)作为微生物采样的诊断方法更为可取。虽然罕见,但如果不及时怀疑,其发病率和死亡率都很高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723d/11361131/08ebd6cc059b/cureus-0016-00000065744-i01.jpg

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