Middleton J, Wells W
Br Med J (Clin Res Ed). 1985 Apr 27;290(6477):1254-5. doi: 10.1136/bmj.290.6477.1254.
Between June and September 1984, district nurses who worked in Coventry were asked to submit returns giving details of the patients for whom they administered vitamin B12 injections. Of 492 patients identified, 382 (78%) were receiving injections more frequently than the recommended three monthly dose of hydroxy-cobalamin. An extra 3751 injections are being administered a year. Four hundred and thirty (88%) of these patients have conditions for which the drug is of proven benefit, so the increased frequency of injections accounts for most of the observed excess. A total of 2000 hours a year of district nurse time is spent with these patients. The nursing service is under increasing strain. Changes in vitamin B12 prescribing alone could make between 600 and 1470 hours available for other patient needs.
1984年6月至9月期间,考文垂地区的社区护士被要求提交报告,详细说明她们为哪些患者注射了维生素B12。在确认的492名患者中,382名(78%)接受注射的频率高于推荐的每三个月一次的羟钴胺剂量。每年额外注射3751次。这些患者中有430名(88%)患有已证实该药物有益的疾病,因此注射频率增加是观察到的过量注射的主要原因。社区护士每年为这些患者花费总计2000小时的时间。护理服务面临的压力越来越大。仅维生素B12处方的改变就可为满足其他患者需求腾出600至1470小时的时间。