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与胫骨、股骨和颌骨同种异体骨移植同时植入的种植体骨整合水平的生物力学评估

Biomechanical Evaluation of the Osseointegration Levels of Implants Placed Simultaneously With Tibia, Femur, and Jaw Allogeneic Bone Grafts.

作者信息

Ozcan Erhan Cahit, Sokmen Kevser, Karasu Necmettin, Bal Ali, Tanrisever Murat, Istek Ozmen, Kirtay Mustafa, Bozoglan Alihan, Dundar Serkan

机构信息

Deparment of Plastic, Esthetic and Reconstructive Surgery, Faculty of Medicine, Firat University, Elazig, Turkiye.

Deprtment of Periodontology, Faculty of Dentistry, Alanya Alaaddin Keykubat University, Antalya, Turkiye.

出版信息

J Craniofac Surg. 2025;36(1):323-327. doi: 10.1097/SCS.0000000000010517. Epub 2024 Aug 30.

Abstract

In implant-supported prosthetic treatments, the jaw bones may not always have enough bone to accommodate implants. Allogeneic grafts can also be preferred as an alternative to autogenous grafts in cases of vertical and horizontal bone deficiencies. The aim of this study is to evaluate the osseointegration levels of lathe-faced titanium implants placed together with allogeneic bone tissue transplants obtained from tibia, femur, and mandible bones using a biomechanical method. Twenty-eight female Sprague Dawley rats were included in the study. The subjects were divided into groups where bone transplantations were performed together with implant placement from the tibia (n=7), femur (n=7), and lower jaw (n=7) regions. Four rats (left and right) were used as donors. Grafts, along with implants, were surgically placed in the corticocancellous part of the metaphyseal parts of the tibia bones of rats. At the end of the 2-week experimental setup, all rats were killed, and the implants and surrounding bone tissues were subjected to biomechanical reverse torque analysis (N/cm), no statistical difference was detected in terms of bone-implant fusion between the groups in which the femur and tibia bones were transplanted ( P >0.05), while the bone-implant fusion value in the group in which the lower jaw bone was transplanted was found to be statistically higher than the femur and tibia bones ( P <0.05). Based on the limited results of this study, it can be thought that the lower jaw allogeneic jawbone has a higher osseointegration potential than allogeneic grafts obtained from the femur and tibia.

摘要

在种植体支持的修复治疗中,颌骨可能并不总是有足够的骨量来容纳种植体。在存在垂直和水平骨缺损的情况下,同种异体移植物也可作为自体移植物的替代选择。本研究的目的是使用生物力学方法评估与从胫骨、股骨和下颌骨获取的同种异体骨组织移植一起植入的车床面钛种植体的骨整合水平。28只雌性斯普拉格-道利大鼠被纳入本研究。将实验对象分为从胫骨(n = 7)、股骨(n = 7)和下颌(n = 7)区域进行骨移植并同时植入种植体的组。4只大鼠(左右各2只)用作供体。将移植物与种植体一起手术植入大鼠胫骨干骺端的皮质骨松质部分。在2周的实验设置结束时,处死所有大鼠,并对种植体和周围骨组织进行生物力学反向扭矩分析(N/cm),在移植股骨和胫骨的组之间,骨-种植体融合方面未检测到统计学差异(P>0.05),而移植下颌骨的组中的骨-种植体融合值在统计学上高于股骨和胫骨(P<0.05)。基于本研究的有限结果,可以认为下颌同种异体骨比从股骨和胫骨获取的同种异体移植物具有更高的骨整合潜力。

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