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同种异体骨环与异种骨环植入物的骨整合水平:一项实验生物力学分析。

Osseointegration Levels of Implants Placed With Allogenic and Xenogenic Bone Ring: An Experimental Biomechanical Analysis.

机构信息

Deparment of Periodontology, Harran University, Faculty of Dentistry.

Deparment of Periodontology, Firat University, Faculty of Dentistry.

出版信息

J Craniofac Surg. 2023 May 1;34(3):926-930. doi: 10.1097/SCS.0000000000009130. Epub 2022 Nov 24.

Abstract

This in vivo study aimed to do a biomechanical analysis of the early period bone-implant connection of titanium implants simultaneously inserted with xsenogenic and allogenic bone ring. In this study, 28 Sprague Dawley female rats were used. Four rats were killed to obtain an allogenic bone ring, and after this, the remaining rats were divided into control (n=8), xsenogenic (n=8), and allogenic (n=8) bone ring groups. Titanium-machined surfaced implants were integrated right tibias of the rats. In controls, only implants were integrated into right tibias. In the greft groups, the implants were integrated simultaneously with bone rings. After 2 weeks of the experimental period, the rats were killed ,and titanium implants and surrounding bone tissues were removed for biomechanic analysis. After biomechanical reverse torque analysis bone-implant connection was determined as Newton/cm 2 ; in controls 3.26 (1.2 to 4.5), in allogenic ring group 3.37 (2 to 4.4), in xsenogenic ring group 5.93 (2.8 to 10). Statistically significant differences were not detected between the groups ( P >0.05). Within the limitation of this study, both allogenic and xsenogenic bone grafts could be successfully used in bone augmentation in implant surgery.

摘要

本体内研究旨在对同时植入异种和同种异体骨环的钛植入物的早期骨-植入物连接进行生物力学分析。本研究使用了 28 只 Sprague Dawley 雌性大鼠。4 只大鼠被处死以获得同种异体骨环,之后,其余大鼠被分为对照组(n=8)、异种(n=8)和同种异体(n=8)骨环组。钛加工表面植入物被整合到大鼠的右侧胫骨中。在对照组中,仅将植入物整合到右侧胫骨中。在移植物组中,同时将植入物与骨环整合。实验期 2 周后,处死大鼠,取出钛植入物和周围骨组织进行生物力学分析。在生物力学反向扭矩分析后,将骨-植入物连接确定为牛顿/厘米 2 ;在对照组中为 3.26(1.2 至 4.5),在同种异体环组中为 3.37(2 至 4.4),在异种环组中为 5.93(2.8 至 10)。组间无统计学差异(P>0.05)。在本研究的限制范围内,同种异体和异种骨移植物均可成功用于植入物手术中的骨增强。

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