Li Fang Fang, Faber Alison, Caleta Jessica M, Goldfarb David M, Sekirov Inna, Prystajecky Natalie A, Srigley Jocelyn A, Mishaal Ram, Jassem Agatha N
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
J Infect Dis. 2025 Feb 20;231(2):490-494. doi: 10.1093/infdis/jiae411.
Guillain-Barré syndrome (GBS) is an acute peripheral neuropathy often preceded by respiratory or gastrointestinal infections, though molecular testing of cerebrospinal fluid is often inconclusive. In a recent case of severe pediatric GBS in British Columbia, Canada, we detected cerebrospinal fluid antibodies against enterovirus D to link GBS with prior enterovirus D68 respiratory infection.
吉兰-巴雷综合征（GBS）是一种急性周围神经病变，通常在呼吸道或胃肠道感染后出现，尽管脑脊液的分子检测结果往往不明确。在加拿大不列颠哥伦比亚省最近一例严重的儿童GBS病例中，我们检测到脑脊液中存在抗肠道病毒D的抗体，从而将GBS与先前的肠道病毒D68呼吸道感染联系起来。
