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纤维蛋白凝块增强高危半月板修复术在高达90%的病例中可能会实现临床愈合。

Fibrin clot augmentation of high-risk meniscal repairs may result in clinical healing in up to 90% of cases.

作者信息

Davies Peter S E, Goldberg Michael, Anderson Jon A, Dabis John, Stillwell Andrew, McMeniman Timothy J, Myers Peter T

机构信息

Brisbane Orthopaedic and Sports Medicine Centre, Level 6 Brisbane Private Hospital, 259 Wickham Terrace, Brisbane, QLD, Australia.

Brisbane Orthopaedic and Sports Medicine Centre, Level 6 Brisbane Private Hospital, 259 Wickham Terrace, Brisbane, QLD, Australia.

出版信息

J ISAKOS. 2024 Dec;9(6):100316. doi: 10.1016/j.jisako.2024.100316. Epub 2024 Aug 30.

Abstract

OBJECTIVE

While meniscal repair is preferable to meniscectomy, some cases may be at higher risk of failure if repaired. Incorporating fibrin clot (FC) into the repair has been proposed to improve healing rates. The purpose of this study was to determine the failure rates, patient reported outcome measures (PROMs) and complications of FC augmented meniscal repair for cases considered to be at higher risk of failure.

METHODS

A retrospective case series of all patients undergoing FC augmented repair of isolated meniscus tears between January 2016 and September 2021 was undertaken. All cases were thought be at higher risk of failure; they included chronic, radial, complex, horizontal cleavage, and tears not in the red-red zone. Patients were excluded if they had a concomitant anterior cruciate ligament (ACL) reconstruction or if the repair was done through an open incision. The primary outcome was clinical failure defined as further repair or debridement. Secondary outcomes were PROMs and surgical complications. PROMs collected were Lysholm score, Knee injury and Osteoarthritis Outcome Score, Oxford Knee Score and the Tegner score.

RESULTS

Fifty one inside-out meniscal repairs using FC were performed in 50 patients (62% male). The mean age was 34 years (range 14-70). The median time from injury to repair was 122 days (range 4-1565). The medial meniscus was repaired in 63% of cases. Tear types included radial (31%) and complex (39%) and 71% of cases included repair of the white-white zone. 16% of cases were revision meniscal repairs. FC was used in 43% of isolated meniscal repairs during the study period. All patients were followed up to a median of 46 months (range 22-87 months). PROMs at a median of 30 months post-operatively showed statistically significant improvements. Five patients (10%) underwent further surgery for failure after median 21 months. Two patients (4%) reported sensory disturbance around their skin wounds, no other complications were reported. 13% of medial meniscal repairs failed, whereas only 5% of lateral meniscal repairs failed (p ​= ​0.4).

CONCLUSIONS

FC augmented meniscal repair performed for tears considered to be at higher risk of failure may result in acceptably low rates of clinical failure.

LEVEL OF EVIDENCE

Level IV, case series.

摘要

目的

虽然半月板修复优于半月板切除术,但某些病例如果进行修复,失败风险可能更高。有人提出在修复中加入纤维蛋白凝块(FC)以提高愈合率。本研究的目的是确定对于被认为失败风险较高的病例,FC增强半月板修复的失败率、患者报告的结局指标(PROMs)和并发症。

方法

对2016年1月至2021年9月期间所有接受FC增强孤立半月板撕裂修复的患者进行回顾性病例系列研究。所有病例被认为失败风险较高;包括慢性、放射状、复杂、水平劈裂以及非红 - 红区的撕裂。如果患者同时进行前交叉韧带(ACL)重建或修复通过开放切口进行,则将其排除。主要结局是临床失败,定义为进一步修复或清创。次要结局是PROMs和手术并发症。收集的PROMs包括Lysholm评分、膝关节损伤和骨关节炎结局评分、牛津膝关节评分和Tegner评分。

结果

50例患者(62%为男性)进行了51次使用FC的由内向外半月板修复。平均年龄为34岁(范围14 - 70岁)。从受伤到修复的中位时间为122天(范围4 - 1565天)。63%的病例修复内侧半月板。撕裂类型包括放射状(31%)和复杂型(39%),71%的病例包括白 - 白区修复。16%的病例是半月板翻修手术。在研究期间,43%的孤立半月板修复使用了FC。所有患者随访至中位时间46个月(范围22 - 87个月)。术后中位30个月时的PROMs显示有统计学意义的改善。5例患者(10%)在中位21个月后因失败接受了进一步手术。2例患者(4%)报告皮肤伤口周围感觉障碍,未报告其他并发症。内侧半月板修复的失败率为13%,而外侧半月板修复的失败率仅为5%(p = 0.4)。

结论

对于被认为失败风险较高的撕裂进行FC增强半月板修复,可能会导致临床失败率低至可接受水平。

证据水平

IV级,病例系列。

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