Costa Giuseppe Gianluca, Grassi Alberto, Zocco Gianluca, Graceffa Angelo, Lauria Michele, Fanzone Giuseppe, Zaffagnini Stefano, Russo Arcangelo
Orthopaedic and Traumatologic Unit, Umberto I Hospital, Azienda Sanitaria Provinciale di Enna, Enna, Italy.
II Orthopaedic and Traumatologic Clinic, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Am J Sports Med. 2022 May;50(6):1742-1752. doi: 10.1177/03635465211015425. Epub 2021 Jun 23.
Meniscal repair has become the treatment of choice for meniscal tears, especially in the subset of bucket-handle meniscal tears (BHMTs). However, a comprehensive estimate of the corresponding failure rate is not available, thus maintaining doubts about the healing potential of these tears. Furthermore, a wide range of factors to predict high failure rates have been reported but with conflicting evidence.
To determine the failure rate after arthroscopic repair of BHMTs as reported in the literature, compare this with the failure rate of simple meniscal tears extracted from the same studies, and analyze the influence of factors previously reported to be predictive of meniscal repair failure.
Systematic review and meta-analysis; Level of evidence, 4.
A systematic search was conducted by 2 independent reviewers using principal bibliographic databases (PubMed, Scopus, Cochrane Library, and EMBASE). After a stepwise exclusion process, 38 articles met the inclusion criteria. Failure rate data were analyzed with a random-effects proportional meta-analysis (weighted for individual study size), and forest plots were constructed to determine any statistically significant differences between BHMTs versus simple tears (longitudinal, radial, or horizontal), medial versus lateral BHMTs, isolated procedures versus repairs with concomitant anterior cruciate ligament reconstruction, and tears in red-red versus red-white zones. Moreover, a meta-regression analysis was conducted to evaluate the effect of patient age and sex, suture technique (in-out or all-inside), time from injury to surgery, mean number of stitches, and length of follow-up on failure rates.
The pooled failure rate was 14.8% (95% CI, 11.3%-18.3%; = 77.2%). A total of 17 studies provided failure rates of both BHMT repairs (46/311 repairs) and simple tear repairs (54/546 repairs), demonstrating a significantly higher failure rate for BHMT repairs (risk ratio [RR] = 1.50; 95% CI, 1.05-2.15; = 0%; = .03). Medial BHMT repairs (RR = 1.94; 95% CI, 1.25-3.01; = 0%; = .003) and isolated repairs (RR = 1.77; 95% CI, 1.15-2.72; = 0%; = .009) had statistically higher risk of failure, but no statistically significant difference was found between tears in red-red versus red-white zones. Among the other factors evaluated with meta-regression, only the mean number of stitches showed a statistically significant effect on failure rates.
Based on the currently available literature, this systematic review provides a reasonably comprehensive analysis of failure rate after arthroscopic BHMT repair; failure is estimated to occur in 14.8% of cases. Medial tears and isolated repairs were the 2 major predictors of failure.
半月板修复已成为半月板撕裂的首选治疗方法,尤其是在桶柄状半月板撕裂(BHMT)亚组中。然而,目前尚无对相应失败率的全面估计,因此人们对这些撕裂的愈合潜力仍存疑虑。此外,已有大量预测高失败率的因素被报道,但证据相互矛盾。
确定文献报道的关节镜下修复BHMT后的失败率,将其与同一研究中提取的单纯半月板撕裂的失败率进行比较,并分析先前报道的预测半月板修复失败的因素的影响。
系统评价和荟萃分析;证据等级,4级。
由2名独立审阅者使用主要文献数据库(PubMed、Scopus、Cochrane图书馆和EMBASE)进行系统检索。经过逐步排除过程,38篇文章符合纳入标准。失败率数据采用随机效应比例荟萃分析(根据各研究规模加权)进行分析,并绘制森林图以确定BHMT与单纯撕裂(纵向、放射状或水平撕裂)、内侧与外侧BHMT、单纯手术与同期前交叉韧带重建修复之间的任何统计学显著差异,以及红白区与红-红区撕裂之间存在的差异。此外还进行了荟萃回归分析,以评估患者年龄和性别、缝合技术(内外缝合或全内缝合)、受伤至手术的时间、平均缝合针数和随访时间对失败率的影响。
汇总失败率为14.8%(95%CI,11.3%-18.3%;I² = 77.2%)。共有17项研究提供了BHMT修复(4亚组/311次修复)和单纯撕裂修复(54/546次修复)的失败率,结果显示BHMT修复的失败率显著更高(风险比[RR]=1.50;95%CI,1.05-2.15;I² = 0%;P = 0.03)。内侧BHMT修复(RR = 1.94;95%CI,1.25-3.01;I² = 0%;P = 0.003)和单纯修复(RR = 1.77;95%CI,1.15-2.72;I² = 0%;P = 0.009)在统计学上有更高的失败风险,但在红-红区与红白区撕裂之间未发现统计学显著差异。在通过荟萃回归评估的其他因素中,只有平均缝合针数对失败率有统计学显著影响。
基于目前可得的文献,本系统评价对关节镜下BHMT修复后的失败率进行了合理全面的分析;估计14.8%的病例会出现失败。内侧撕裂和单纯修复是失败的两个主要预测因素。