Engineering Research Center of Health Food Design & Nutrition Regulation, School of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.
Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi University for Nationalities, Nanning, China.
Int J Biol Macromol. 2024 Nov;279(Pt 2):135191. doi: 10.1016/j.ijbiomac.2024.135191. Epub 2024 Aug 29.
Lotus (Nelumbo nucifera), belonging to the family of Nelumbonaceae, is a beautiful aquatic perennial plant. It has been used as an ancient horticulture plant and famous agricultural crop for thousands of years. Modern phytochemical and pharmacological experiments have proved that polysaccharide is one of the most pivotal bioactive constituents of lotus. Hence, the systematic review covering the fundamental research advances and developing prospects of N. nucifera polysaccharides (NNPs) is an urgent demand to provide theoretical basis for their further research and application. The present review summarizes current emerging research progresses on the polysaccharides isolated from lotus, and it focuses on advanced extraction and purification methods, unique structural features, engaging biological activities, potential molecular mechanisms, as well as the relationship of structure and activity of NNPs. This review sheds light on the potential values of NNPs in affording functionally bioactive agents in food industry or therapeutically effective medicines for health care. In addition, this review will provide valuable insights for further commercial product development and promising industrial application of NNPs in both of the fundamental research communities and food or pharmaceutical industries in future.
荷花（Nelumbo nucifera），属于莲科，是一种美丽的水生多年生植物。千百年来，它一直被用作古代园艺植物和著名的农业作物。现代植物化学和药理学实验证明，多糖是荷花中最关键的生物活性成分之一。因此，对荷花多糖（NNPs）的基础研究进展和发展前景进行系统综述，是对其进一步研究和应用提供理论基础的迫切需求。本综述总结了从荷花中分离得到的多糖的最新研究进展，重点介绍了先进的提取和纯化方法、独特的结构特征、引人注目的生物活性、潜在的分子机制，以及 NNPs 的结构与活性关系。本文综述了 NNPs 在食品工业中提供功能性生物活性物质或在医疗保健中提供治疗有效药物方面的潜在价值。此外，本综述将为进一步的商业产品开发提供有价值的见解，并为 NNPs 在基础研究界以及食品或制药行业的未来的有希望的工业应用提供有价值的见解。
