Dai Guona, Wang Jiale, Zheng Jiamei, Xia Conglong, Wang Yaping, Duan Baozhong
College of Pharmaceutical Science, Dali University, Dali, China.
Formula-Pattern Research Center, School of Traditional Chinese Medicine, Jinan University, Guangzhou, Guangdong, China.
Front Nutr. 2023 Jun 28;10:1171004. doi: 10.3389/fnut.2023.1171004. eCollection 2023.
Lotus is a famous plant of the food and medicine continuum for millennia, which possesses unique nutritional and medicinal values. Polysaccharides are the main bioactive component of lotus and have been widely used as health nutritional supplements and therapeutic agents. However, the industrial production and application of lotus polysaccharides (LPs) are hindered by the lack of a deeper understanding of the structure-activity relationship (SAR), structural modification, applications, and safety of LPs. This review comprehensively comments on the extraction and purification methods and structural characteristics of LPs. The SARs, bioactivities, and mechanisms involved are further evaluated. The potential application and safety issues of LPs are discussed. This review provides valuable updated information and inspires deeper insights for the large scale development and application of LPs.
几千年来，莲花是一种著名的兼具食品和药物双重属性的植物，具有独特的营养和药用价值。多糖是莲花的主要生物活性成分，已被广泛用作健康营养补充剂和治疗剂。然而，由于对莲多糖（LPs）的构效关系（SAR）、结构修饰、应用和安全性缺乏更深入的了解，阻碍了莲多糖的工业化生产和应用。本文综述全面评述了莲多糖的提取纯化方法和结构特征，进一步评估了其构效关系、生物活性及相关机制，讨论了莲多糖的潜在应用和安全性问题。本文综述提供了有价值的最新信息，并为莲多糖的大规模开发和应用提供了更深刻的见解。
