Biglan A W, Milley J R, Brown D R, Reynolds J D
J Pediatr Ophthalmol Strabismus. 1985 Mar-Apr;22(2):44-50. doi: 10.3928/0191-3913-19850301-03.
We examined the eyes of all infants in our Neonatal Intensive Care Unit from 1979 to 1981 who were premature and/or had exposure to increased ambient oxygen. From these 1,012 neonates, 19 were found to have Grade III or worse acute retinopathy of prematurity (ROP) in at least one eye. We studied the graphic relationship of the mean daily values for blood Pc02, Pa02, PC02, and pH and the production of retinopathy of prematurity in these infants and compared the results with a similar group of infants who had similar birthweight, gestational age and Vitamin E administration. The comparison group patients were in the hospital during this same period of time and did not have Grade III ROP. There was no characteristic level, peak or pattern of these values that could identify or predict which infants would develop ROP.
我们检查了1979年至1981年期间在我们新生儿重症监护病房的所有早产和/或暴露于高环境氧的婴儿的眼睛。在这1012名新生儿中，发现19名至少一只眼睛患有III级或更严重的早产儿视网膜病变（ROP）。我们研究了这些婴儿血液中PCO₂、PaO₂、PC0₂和pH的平均日值与早产儿视网膜病变发生之间的图表关系，并将结果与一组出生体重、胎龄和维生素E给药情况相似的婴儿进行了比较。对照组患者在同一时期住院，没有III级ROP。这些值没有能够识别或预测哪些婴儿会发生ROP的特征水平、峰值或模式。
