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神经损伤对损伤炎症反应的影响。

The effect of nerve lesions on the inflammatory response to injury.

作者信息

Helme R D, Andrews P V

出版信息

J Neurosci Res. 1985;13(3):453-9. doi: 10.1002/jnr.490130311.

DOI:10.1002/jnr.490130311
PMID:3921721
Abstract

The effects of surgical denervation, capsaicin, and 6-Hydroxydopamine pretreatment on the inflammatory response to thermal injury have been investigated in the rat. Surgical denervation and capsaicin pretreatment reduced the cellular and exudative reactions to the injury. 6-Hydroxydopamine appeared to have a selective effect on the exudative reaction only. The effects of surgical denervation are partly explained by local and systemic effects of the procedure.

摘要

在大鼠中研究了手术去神经、辣椒素和6-羟基多巴胺预处理对热损伤炎症反应的影响。手术去神经和辣椒素预处理减少了对损伤的细胞和渗出反应。6-羟基多巴胺似乎仅对渗出反应有选择性作用。手术去神经的作用部分可由该手术的局部和全身作用来解释。

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