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功能性物质水凝胶递药系统用于精准营养

Hydrogel delivery systems of functional substances for precision nutrition.

机构信息

Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education. School of Food and Health, Beijing Technology & Business University, Beijing, P.R. China.

出版信息

Adv Food Nutr Res. 2024;112:301-345. doi: 10.1016/bs.afnr.2024.07.001. Epub 2024 Aug 9.

Abstract

Hydrogel delivery systems based on polysaccharides and proteins have the ability to protect functional substances from chemical degradation, control/target release, and increase bioavailability. This chapter summarizes the recent progress in the utilization of hydrogel delivery systems for nutritional interventions. Various hydrogel delivery systems as well as their preparation, structure, and properties are given. The applications for the encapsulation, protection, and controlled delivery of functional substances are described. We also discuss their potential and challenges in managing chronic diseases such as inflammatory bowel disease, obesity, liver disease, and cancer, aiming at providing theoretical references for exploring novel hydrogel delivery systems and their practical prospects in precise nutritional interventions.

摘要

基于多糖和蛋白质的水凝胶输送系统具有保护功能物质免受化学降解、控制/靶向释放和提高生物利用度的能力。本章总结了水凝胶输送系统在营养干预中的最新应用进展。给出了各种水凝胶输送系统及其制备、结构和性能。描述了它们在封装、保护和控制功能物质释放方面的应用。我们还讨论了它们在管理炎症性肠病、肥胖、肝病和癌症等慢性疾病方面的潜力和挑战,旨在为探索新型水凝胶输送系统及其在精准营养干预中的实际前景提供理论参考。

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