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功能性物质的微胶囊递送系统用于精准营养。

Microencapsule delivery systems of functional substances for precision nutrition.

机构信息

College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi, P.R. China.

College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi, P.R. China.

出版信息

Adv Food Nutr Res. 2024;112:199-255. doi: 10.1016/bs.afnr.2024.05.004. Epub 2024 Jun 18.

Abstract

Microencapsulation, a typical core-shell structure technology, encapsulates functional active ingredients for protection, controlled release, and targeted delivery. In precise nutrition, the focus is on utilizing microcapsule delivery systems for personalized dietary supplements and disease intervention. This chapter outlines the morphological structure of microcapsules, common wall materials, and preparation techniques. It discusses the characteristics of different hydrophilic and lipophilic functional factors and their function as dietary supplements. The role of microencapsulation on the controlled release, odor masking, and enhanced bioavailability of functional factors is explored. Additionally, the application of microcapsule delivery systems in nutritional interventions for diseases like inflammatory bowel disease, alcoholic/fatty liver disease, diabetes, and cancer is introduced in detail. Lastly, the chapter proposes the future developments of anticipation in responsive wall materials for precise nutrition interventions, including both challenges and opportunities.

摘要

微胶囊化是一种典型的核壳结构技术,可用于保护、控制释放和靶向递送功能性活性成分。在精准营养中,重点是利用微胶囊递送系统来提供个性化的膳食补充剂和疾病干预。本章概述了微胶囊的形态结构、常见壁材和制备技术。讨论了不同亲水性和疏水性功能因子的特性及其作为膳食补充剂的功能。探讨了微胶囊化对功能因子的控制释放、掩味和提高生物利用度的作用。此外,还详细介绍了微胶囊递送系统在炎症性肠病、酒精性/脂肪肝疾病、糖尿病和癌症等疾病的营养干预中的应用。最后,本章提出了针对精准营养干预的响应性壁材的未来发展预期,包括挑战和机遇。

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