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苹果汁摄入对尿中抗坏血酸排泄的抑制作用:健康日本受试者的双盲随机交叉研究。

Suppressive Effect of Apple Juice Intake on Urinary Excretion of Ascorbic Acid: Unblinded Randomized Crossover Study in Healthy Japanese Subjects.

机构信息

Department of Nutrition, Aomori University of Health and Welfare.

出版信息

J Nutr Sci Vitaminol (Tokyo). 2024;70(4):359-363. doi: 10.3177/jnsv.70.359.

DOI:10.3177/jnsv.70.359
PMID:39218698
Abstract

Ascorbic acid is essential for human health. As this vitamin is water-soluble, it cannot be stored in the body for a long time and is easily excreted in urine; therefore, it is necessary to ingest it in sufficient amounts every day. The fact that apples retain ascorbic acid in human bodies are known; however, this has not been experimentally demonstrated/documented. In this study, to clarify the effect of apple juice ingestion on the urinary excretion of ascorbic acid, we compared urinary ascorbic acid excretion in healthy women administered ascorbic acid alone or with apple juice. The experimental design was an unblinded randomized crossover study. Subjects ingested ascorbic acid in apple juice or ascorbic acid with water. Urine was collected after ingestion, and urinary ascorbic acid was measured. When ascorbic acid was ingested with apple juice, urinary excretion of ascorbic acid was significantly suppressed compared to when ascorbic acid was ingested alone. This suggests that apple juice intake can help retain ascorbic acid in the body.

摘要

抗坏血酸对人体健康至关重要。由于这种维生素是水溶性的,因此不能在体内长时间储存,很容易随尿液排出体外;因此,每天必须摄入足够的量。众所周知,苹果能在人体中保留抗坏血酸;然而,这尚未经过实验证明/记录。在这项研究中,为了阐明摄入苹果汁对尿液中抗坏血酸排泄的影响,我们比较了单独摄入抗坏血酸或同时摄入抗坏血酸和苹果汁的健康女性的尿液中抗坏血酸排泄情况。实验设计为非盲随机交叉研究。受试者摄入苹果汁中的抗坏血酸或水中的抗坏血酸。摄入后收集尿液,并测量尿液中的抗坏血酸。当与苹果汁一起摄入抗坏血酸时,与单独摄入抗坏血酸相比,尿液中抗坏血酸的排泄明显受到抑制。这表明摄入苹果汁有助于在体内保留抗坏血酸。

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