1Silesian University of Technology, Faculty of Biomedical Engineering, Department of Biomaterials and Medical Device Engineering, Zabrze, Poland.
2Polish Academy of Science, Centre of Polymer and Carbon Materials, Zabrze, Poland.
Acta Bioeng Biomech. 2024 May 16;26(1):121-132. doi: 10.37190/abb-02351-2023-03. Print 2024 Jun 1.
: Titanium alloys are among the most widely used materials in medicine, especially in orthopedics. However, their use requires the application of an appropriate surface modification method to improve their properties. Such methods include anodic oxidation and the application of polymer coatings, which limit the release of alloying element ions. In addition, biodegradable polymer coatings can serve as a carrier for drugs and other substances. The paper presents the results of research on the physical properties of biodegradable polymer coatings containing nanoparticle hydroxyapatite on a titanium alloy substrate. : A PLGA coating was used in the tests. The coatings on the substrate of the anodized Ti6Al7Nb alloy were applied by ultrasonic spray coating. The tests were carried out for coatings with various hydroxyapatite content (5, 10, 15, 20%) and thickness resulting from the number of layers applied (5, 10, 15 layers). The scope of the research included microscopic observations using scanning electron microscopy, topography tests with optical profilometry, structural studies using X-ray diffraction, as well as wettability and adhesion tests. : The results shows that with the use of ultrasonic spray coating system is possible to obtain the continuous coatings containing hydroxyapaptite. : The properties of the coating can be controlled by changing the percentage of hydroxyapatite and the number of layers of which the coating is composed.
钛合金是医学领域（尤其是骨科）中应用最广泛的材料之一。然而，其应用需要采用适当的表面改性方法来改善其性能。此类方法包括阳极氧化和聚合物涂层的应用，这限制了合金元素离子的释放。此外，可生物降解的聚合物涂层可用作药物和其他物质的载体。本文介绍了在钛合金基底上含有纳米羟基磷灰石的可生物降解聚合物涂层物理性能的研究结果。在测试中使用了 PLGA 涂层。在经过阳极氧化处理的 Ti6Al7Nb 合金基底上的涂层是通过超声喷涂涂层法施加的。测试是针对具有不同羟基磷灰石含量（5、10、15、20%）和因施加的层数（5、10、15 层）而导致的涂层厚度进行的。研究范围包括使用扫描电子显微镜进行微观观察、使用光学轮廓仪进行形貌测试、使用 X 射线衍射进行结构研究，以及润湿性和附着力测试。结果表明，使用超声喷涂涂层系统可以获得含有羟基磷灰石的连续涂层。通过改变羟基磷灰石的百分比和涂层的层数，可以控制涂层的性能。
