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How to Build a Successful Phase I Clinical Trials Unit: Lessons Based on the MD Anderson Cancer Center Experience.

作者信息

Kurzrock Razelle, Hong David

机构信息

Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

WIN Consortium, Paris, France.

出版信息

J Immunother Precis Oncol. 2024 Aug 19;7(3):142-149. doi: 10.36401/JIPO-23-243. eCollection 2024 Aug.

DOI:10.36401/JIPO-23-243
PMID:39220000
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11361344/
Abstract
摘要

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Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy.分子肿瘤委员会的真实世界数据表明,采用精准 N-of-One 策略可改善预后。
Nat Commun. 2020 Oct 2;11(1):4965. doi: 10.1038/s41467-020-18613-3.
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Review of precision cancer medicine: Evolution of the treatment paradigm.精准肿瘤医学述评:治疗范式的演变。
Cancer Treat Rev. 2020 Jun;86:102019. doi: 10.1016/j.ctrv.2020.102019. Epub 2020 Mar 31.
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Clin Cancer Res. 2017 Mar 15;23(6):1414-1421. doi: 10.1158/1078-0432.CCR-16-2439. Epub 2017 Mar 8.
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Modifying the Clinical Research Infrastructure at a Dedicated Clinical Trials Unit: Assessment of Trial Development, Activation, and Participant Accrual.在专门的临床试验单位修改临床研究基础设施:试验开发、启动及受试者招募评估
Clin Cancer Res. 2017 Mar 15;23(6):1407-1413. doi: 10.1158/1078-0432.CCR-16-1936. Epub 2016 Nov 16.
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Cancer Therapy Directed by Comprehensive Genomic Profiling: A Single Center Study.基于全面基因组分析的癌症治疗:单中心研究。
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Personalized medicine in a phase I clinical trials program: the MD Anderson Cancer Center initiative.个体化医学在 I 期临床试验项目中的应用:MD 安德森癌症中心的计划。
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