原发性结肠腺癌合并十二指肠神经内分泌肿瘤：一例病例报告及文献复习
Primary coexisting adenocarcinoma of the colon and neuroendocrine tumor of the duodenum: A case report and review of the literature.
作者信息
Fei Song, Wu Wei-Dong, Zhang Han-Shuo, Liu Shao-Jie, Li Dan, Jin Bo
机构信息
Department of Thoracic and Cardiovascular Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou 510000, Guangdong Province, China.
Department of Gastrointestinal Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou 510000, Guangdong Province, China.
出版信息
World J Gastrointest Surg. 2024 Aug 27;16(8):2724-2734. doi: 10.4240/wjgs.v16.i8.2724.
BACKGROUND
Neuroendocrine tumors (NETs) arise from the body's diffuse endocrine system. Coexisting primary adenocarcinoma of the colon and NETs of the duodenum (D-NETs) is a rare occurrence in clinical practice. The classification and treatment criteria for D-NETs combined with a second primary cancer have not yet been determined.
CASE SUMMARY
We report the details of a case involving female patient with coexisting primary adenocarcinoma of the colon and a D-NET diagnosed by imaging and surgical specimens. The tumors were treated by surgery and four courses of chemotherapy. The patient achieved a favorable clinical prognosis.
CONCLUSION
Coexisting primary adenocarcinoma of the colon and D-NET were diagnosed by imaging, laboratory indicators, and surgical specimens. Surgical resection combined with chemotherapy was a safe, clinically effective, and cost-effective treatment.
背景
神经内分泌肿瘤（NETs）起源于人体的弥散内分泌系统。临床实践中，结肠原发性腺癌与十二指肠神经内分泌肿瘤（D-NETs）并存的情况较为罕见。D-NETs合并第二原发性癌症的分类及治疗标准尚未确定。
病例摘要
我们报告了一例女性患者的详细情况，该患者经影像学和手术标本诊断为结肠原发性腺癌与D-NETs并存。肿瘤通过手术及四个疗程的化疗进行治疗。患者获得了良好的临床预后。
结论
通过影像学、实验室指标及手术标本诊断出结肠原发性腺癌与D-NETs并存。手术切除联合化疗是一种安全、临床有效的且具有成本效益的治疗方法。
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