Gomà Carles, Henkner Katrin, Jäkel Oliver, Lorentini Stefano, Magro Giuseppe, Mirandola Alfredo, Placidi Lorenzo, Togno Michele, Vidal Marie, Vilches-Freixas Gloria, Wulff Jörg, Safai Sairos
Institute of Cancer and Blood Diseases, Hospital Clínic Barcelona, Barcelona, Spain.
Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.
Phys Imaging Radiat Oncol. 2024 Aug 5;31:100621. doi: 10.1016/j.phro.2024.100621. eCollection 2024 Jul.
Proton therapy (PT) is an advancing radiotherapy modality increasingly integrated into clinical settings, transitioning from research facilities to hospital environments. A critical aspect of the commissioning of a proton pencil beam scanning delivery system is the acquisition of experimental beam data for accurate beam modelling within the treatment planning system (TPS). These guidelines describe in detail the acquisition of proton pencil beam modelling data. First, it outlines the intrinsic characteristics of a proton pencil beam-energy distribution, angular-spatial distribution and particle number. Then, it lists the input data typically requested by TPSs. Finally, it describes in detail the set of experimental measurements recommended for the acquisition of proton pencil beam modelling data-integrated depth-dose curves, spot maps in air, and reference dosimetry. The rigorous characterization of these beam parameters is essential for ensuring the safe and precise delivery of proton therapy treatments.
质子治疗（PT）是一种不断发展的放射治疗方式，越来越多地融入临床环境，正从研究机构过渡到医院环境。质子笔形束扫描输送系统调试的一个关键方面是获取实验束流数据，以便在治疗计划系统（TPS）中进行精确的束流建模。本指南详细描述了质子笔形束建模数据的获取。首先，概述了质子笔形束的内在特性——能量分布、角空间分布和粒子数。然后，列出了TPS通常要求的输入数据。最后，详细描述了为获取质子笔形束建模数据而推荐的一组实验测量——综合深度剂量曲线、空气中的光斑图和参考剂量测定。对这些束流参数进行严格表征对于确保质子治疗的安全和精确实施至关重要。
