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通过动态调整优化参数,利用自动微调过程优化容积调强弧形放疗前列腺计划。

Optimizing volumetric modulated arc therapy prostate planning using an automated Fine-Tuning process through dynamic adjustment of optimization parameters.

作者信息

Cavus Hasan, Rondagh Thierry, Jankelevitch Alexandra, Tournel Koen, Orlandini Marc, Bulens Philippe, Delombaerde Laurence, Geens Kenny, Crijns Wouter, Reniers Brigitte

机构信息

Department of Radiation Oncology, Jessa Hospital, 3500 Hasselt, Belgium.

Limburg Oncology Center, 3500 Hasselt, Belgium.

出版信息

Phys Imaging Radiat Oncol. 2024 Aug 3;31:100619. doi: 10.1016/j.phro.2024.100619. eCollection 2024 Jul.

DOI:10.1016/j.phro.2024.100619
PMID:39220116
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11363496/
Abstract

In radiotherapy treatment planning, optimization is essential for achieving the most favorable plan by adjusting optimization criteria. This study introduced an innovative approach to automatically fine-tune optimization parameters for volumetric modulated arc therapy prostate planning, ensuring all constraints were met. A knowledge-based planning model was invoked, and the fine-tuning process was applied through an in-house developed script. Among 25 prostate plans, this fine-tuning increased the number of plans meeting all constraints from 10/25 to 22/25, with a reduction in mean monitor units per gray without increasing plan's complexity. This automation improved efficiency by saving time and resources in treatment planning.

摘要

在放射治疗治疗计划中,优化对于通过调整优化标准来实现最有利的计划至关重要。本研究引入了一种创新方法,用于自动微调容积调强弧形治疗前列腺计划的优化参数,确保满足所有约束条件。调用了基于知识的计划模型,并通过内部开发的脚本应用微调过程。在25个前列腺计划中,这种微调使满足所有约束条件的计划数量从10/25增加到22/25,同时在不增加计划复杂性的情况下,每灰度的平均监测单位数减少。这种自动化通过节省治疗计划中的时间和资源提高了效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89c6/11363496/48c90f94c065/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89c6/11363496/48c90f94c065/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89c6/11363496/48c90f94c065/gr1.jpg

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本文引用的文献

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Revolutionizing radiation therapy: the role of AI in clinical practice.颠覆放射治疗:人工智能在临床实践中的作用。
J Radiat Res. 2024 Jan 19;65(1):1-9. doi: 10.1093/jrr/rrad090.
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Machine learning-based automatic proton therapy planning: Impact of post-processing and dose-mimicking in plan robustness.基于机器学习的自动质子治疗计划:后处理和剂量模拟对计划稳健性的影响。
Med Phys. 2023 Jul;50(7):4480-4490. doi: 10.1002/mp.16408. Epub 2023 Apr 20.
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Validation of RapidPlan Knowledge-Based Model for Volumetric-Modulated Arc Therapy in Prostate Cancer.
基于知识的快速计划模型在前列腺癌容积调强弧形放疗中的验证
J Med Phys. 2022 Jul-Sep;47(3):250-255. doi: 10.4103/jmp.jmp_138_21. Epub 2022 Nov 8.
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Advances in Automated Treatment Planning.自动化治疗计划的进展。
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Evaluation of an automated template-based treatment planning system for radiotherapy of anal, rectal and prostate cancer.基于模板的自动化治疗计划系统在肛管癌、直肠癌和前列腺癌放射治疗中的评估
Tech Innov Patient Support Radiat Oncol. 2022 Apr 12;22:30-36. doi: 10.1016/j.tipsro.2022.04.001. eCollection 2022 Jun.
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Assessment of efficacy in automated plan generation for Varian Ethos intelligent optimization engine.评估瓦里安 Ethos 智能优化引擎自动计划生成的疗效。
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