Department of Hand Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 710000, People's Republic of China.
Int J Nanomedicine. 2024 Aug 27;19:8815-8830. doi: 10.2147/IJN.S476006. eCollection 2024.
Diabetic wounds pose a significant challenge in modern healthcare due to their chronic and complex nature, often resulting in delayed healing, infections, and, in severe cases, amputations. In recent years, nanotherapeutic approaches have emerged as promising strategies to address the unique pathophysiological characteristics of diabetic wounds. This review paper provides a comprehensive overview of the latest advancements in nanotherapeutics for diabetic wound treatment. We discuss various nanomaterials and delivery systems employed in these emerging therapies. Furthermore, we explore the integration of biomaterials to enhance the efficacy of nanotherapeutic interventions. By examining the current state-of-the-art research, challenges, and prospects, this review aims to offer valuable insights for researchers, clinicians, and healthcare professionals working in the field of diabetic wound care.
糖尿病伤口由于其慢性和复杂的性质，对现代医疗保健构成了重大挑战，往往导致愈合延迟、感染，在严重的情况下，还会导致截肢。近年来，纳米治疗方法作为一种有前途的策略，已经出现，以解决糖尿病伤口的独特病理生理特征。本文综述了纳米治疗糖尿病伤口的最新进展。我们讨论了这些新兴疗法中使用的各种纳米材料和输送系统。此外，我们还探讨了生物材料的整合，以提高纳米治疗干预的效果。通过检查当前的最新研究、挑战和前景，本综述旨在为从事糖尿病伤口护理领域的研究人员、临床医生和医疗保健专业人员提供有价值的见解。
