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记忆的守护者:老龄化社会中早期痴呆筛查的紧迫性

Guardians of memory: The urgency of early dementia screening in an aging society.

作者信息

Hu Xiqi, Ma Ya-Nan, Karako Kenji, Song Peipei, Tang Wei, Xia Ying

机构信息

Department of Neurosurgery, Haikou Affiliated Hospital of Central South University Xiangya School of Medicine, Haikou, China.

Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

出版信息

Intractable Rare Dis Res. 2024 Aug 31;13(3):133-137. doi: 10.5582/irdr.2024.01026.

Abstract

The global aging population has led to a significant rise in the prevalence of age-related non-communicable diseases such as dementia and other cognitive disorders. In 2019, there were 57.4 million people with dementia worldwide, and this number is projected to triple by 2050. Intervening in and managing 12 potentially modifiable dementia risk factors can prevent or delay the onset and progression of about 40% of dementia cases. Neuroimaging, biomarkers, and advanced neuropsychological testing offer promising pathways for the early detection of dementia. Emphasis should be placed on educating the public about the importance of brain health and the early signs of cognitive impairment, as well as promoting dementia prevention measures. Adopting a healthy lifestyle - including a balanced diet, regular physical exercise, active social engagement, cognitive activities, and avoiding smoking and excessive alcohol consumption - can help reduce the risk of cognitive decline and prevent cognitive disorders. Government policies on dementia prevention and health care, along with early and regular dementia screening programs, can enhance the early identification and management of individuals at risk. In addition, integrating cognitive health assessments into routine medical check-ups is essential for the early screening and management of dementia.

摘要

全球老龄化人口导致痴呆症和其他认知障碍等与年龄相关的非传染性疾病的患病率显著上升。2019年,全球有5740万人患有痴呆症,预计到2050年这一数字将增至三倍。干预和管理12种可能可改变的痴呆症风险因素可以预防或延缓约40%的痴呆症病例的发病和进展。神经影像学、生物标志物和先进的神经心理学测试为痴呆症的早期检测提供了有前景的途径。应重视向公众宣传大脑健康的重要性和认知障碍的早期迹象,以及推广痴呆症预防措施。采取健康的生活方式——包括均衡饮食、定期体育锻炼、积极参与社交活动、进行认知活动以及避免吸烟和过量饮酒——有助于降低认知能力下降的风险并预防认知障碍。政府关于痴呆症预防和医疗保健的政策,以及早期和定期的痴呆症筛查项目,可以加强对高危个体的早期识别和管理。此外,将认知健康评估纳入常规体检对于痴呆症的早期筛查和管理至关重要。

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